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Research into Mechanical testing of ex vivo lenses at the Ophthalmic Engineering lab at the Department of Engineering Science, University of Oxford

Mechanical testing of ex vivo lenses

Research is underway, in collaboration with the Barraquer Institute in Barcelona, on the mechanical behaviour of ex vivo lenses. Much of this work relates to observations of lens performance in radial stretching tests.

Key publications

Michael, R., D'Antin, J.C., Pinilla Cortés, L., Burd, H.J., Sheil, B. & Barraquer, R.I. (2021)  Deformations and ruptures in human lenses with cortical cataract subjected to ex vivo simulated accommodation. 62(1):12. IOVS https://doi.org/10.1167/iovs.62.1.12

Pellegrino, A., Burd, H. J., Cortés, L. P., D'Antin, J. C., Petrinic, N., Barraquer, R. I., & Michael, R. (2018). Anterior lens capsule strains during simulated accommodation in porcine eyes. Experimental Eye Research, 168, 19-27. https://doi.org/10.1016/j.exer.2017.12.008

Burd, H. J., Montenegro, G. A., Cortés, L. P., Barraquer, R. I., & Michael, R. (2017). Equatorial wrinkles in the human lens capsule. Experimental eye research, 159, 77-86. https://doi.org/10.1016/j.exer.2017.02.004

Cortes, L.P., Burd, H.J., Montenegro, G.A., D'Antin, J.C., Mikielewicz, M., Barraquer, R.I., & Michael, R. (2015). Experimental protocols for ex vivo lens stretching tests to investigate the biomechanics of the human accommodation apparatus. Investigative Ophthalmology & Visual Science, 56 (5), 2926-2932. https://doi.org/10.1167/iovs.14-15744