Biomedical Image Analysis
Biomedical Image Analysis
to the Oxford Biomedical Image Analysis (BioMedIA) cluster
The Oxford Biomedical Image Analysis (BioMedIA) cluster is an academic group of faculty, postdoctoral researchers, software engineers, support staff and research students that develop medical imaging and image analysis algorithms and tools that aim to improve image-based diagnostics, therapies and monitoring technologies in hospitals and primary care, and for both western world and global health care settings. The breadth of our interests span all major clinical imaging modalities (particularly magnetic resonance imaging, ultrasound imaging, endoscopy imaging, histopathology), multi-modal imaging (imaging and audio, imaging and gaze tracking, imaging and electrocardiogram) and microscopy.
We conduct inter-disciplinary translational research with clinical partners in Oxford and elsewhere in the UK and overseas in clinical domains of application ranging from fetal development, to oncology, respiratory medicine, gastroenterology, neurology and cardiovascular medicine.
We have a strong tradition of postgraduate research training and welcome enquiries from prospective research students. Current research students are enrolled on one of a number of programmes including: the DPhil in Engineering Science, the Centre for Doctoral Training in Health Data Sciences, and the National Institutes of Health Oxford-Cambridge Scholars Programme.
We work on creating image acquisition We work on creating image acquisition and analysis methods for obtaining quantitative physiological information from both healthy and diseased tissue. We are particularly interested in imaging vascular pathologies, hypoxia in tumours, and neurodegeneration. Our research incorporates a variety of MRI techniques including Oxygen Enhanced MRI, arterial spin labelling, T1, T2 and T2 mapping, and diffusion imaging. In addition, we have ongoing research using transcranial Doppler ultrasound, near infrared spectroscopy, pupillometry, PET and CT. The group is working towards the clinical translation of these emerging methods, and thus we concentrate on using short, patient-friendly paradigms.
Our research focuses on the development of biomedical image analysis algorithms, with an emphasis on the combination with computational models, and applications on cardiac and pulmonary medicine.
Our current research themes involve the development of tools to analyse images of the fetal brain at different stages in pregnancy for the purpose of pre-birth diagnosis of conditions such as malnutrition and fetal alcohol syndrome. More information about ongoing projects may be found on this website.
The Noble group conducts research on machine learning applied to fetal ultrasound image analysis, cardiac magnetic resonance image analysis, and cell image analysis. A major focus of the group’s research is ultrasound. We are measuring at scale how operators scan, by recording eye and probe tracking, ultrasound video and audio in the clinic. This enables us to develop machine learning models to characterise operator skill, and to build multi-modal ultrasound assistive technologies to support non-experts to scan. We are also developing low-cost ultrasound technologies empowered by deep learning based algorithms for pregnancy risk assessment in collaboration with partners in Africa and India. Our overall ambition is to advance ultrasound towards it becoming an accessible medical imaging technology to all medical professionals worldwide.
Motion is a massive barrier in cancer imaging hampering developments in cancer research and treatment. My research work has comprised the development of accurate, thus complex and realistic but still computationally efficient, models of organ motion, and has established a solid foundation to reliable quantitative cancer image analysis.
The aim of our research is to enhance our understanding of complex biological processes through the analysis of image data that has been acquired at the microscopic scale. We develops algorithms and methods that enable the quantification of a broad range of phenotypical alterations, the precise localisation of signalling events, and the ability to correlate such events in the context of the biological specimen.