Publications

BibTeX

@article{theoxfordneedle-2023/12,
  title={The Oxford Needle Experience (ONE) scale: a UK-based and US-based online mixed-methods psychometric development and validation study of an instrument to assess needle fear, attitudes and expectations in the general public},
  author={Kantor J, Vanderslott S, Morrison M, Pollard AJ & Carlisle RC},
  journal={BMJ Open},
  volume={13},
  number={e074466},
  publisher={BMJ Publishing Group},
  year = "2023"
}

BibTeX

@article{sonosensitiveca-2023/11,
  title={Sonosensitive cavitation nuclei-a customisable platform technology for enhanced therapeutic delivery},
  author={Lyons B, Balkaran JPR, Dunn-Lawless D, Lucian V, Keller SB et al.},
  journal={Molecules},
  volume={28},
  number={7733},
  publisher={MDPI},
  year = "2023"
}

BibTeX

@article{hpbpexvivonormo-2023/11,
  title={HPB P26 Ex vivo normothermic perfusion of liver, kidney and spleen to predict human pharmacokinetics and assess drug delivery},
  author={Clark T, Bau L, Dengu F, Voyce D, Friend P et al.},
  journal={British Journal of Surgery},
  volume={110},
  publisher={Oxford University Press},
  year = "2023"
}

BibTeX

@article{cavitationmedia-2023/9,
  title={Cavitation-mediated transcutaneous delivery of protein and nucleotide-based antigen for rapid high-level immune responses},
  author={Hettinga JK, Lyons B, Balkaran J, Rijal P, Dunn‐Lawless D et al.},
  journal={Advanced Therapeutics},
  volume={6},
  number={2300102},
  publisher={Wiley},
  year = "2023"
}

BibTeX

@article{clinicaltrialpr-2023/9,
  title={Clinical trial protocol for PanDox: a phase I study of targeted chemotherapy delivery to non-resectable primary pancreatic tumours using thermosensitive liposomal doxorubicin (ThermoDox®) and focused ultrasound},
  author={Spiers L, Gray M, Lyon P, Sivakumar S, Bekkali N et al.},
  journal={BMC Cancer},
  volume={23},
  number={896},
  publisher={BioMed Central},
  year = "2023"
}

BibTeX

@article{cavitationmedia-2023/8,
  title={Cavitation-mediated immunomodulation and its use with checkpoint inhibitors},
  author={Maardalen M, Carlisle R & Coussios C},
  journal={Pharmaceutics},
  volume={15},
  number={2110},
  publisher={MDPI},
  year = "2023"
}

BibTeX

@article{cavitationmedia-2023/8,
  title={Cavitation-Mediated Immunomodulation and Its Use with Checkpoint Inhibitors.},
  author={Maardalen M, Carlisle R & Coussios C},
  journal={Pharmaceutics},
  volume={15},
  pages={2110},
  year = "2023"
}

BibTeX

@article{cavitationmedia-2023/,
  title={Cavitation-Mediated Transcutaneous Delivery of Protein and Nucleotide-based Antigen for Rapid High-level Immune Responses},
  author={Hettinga JK, Lyons B, Balkaran J, Rijal P, Dunn-Lawless D et al.},
  journal={ADVANCED THERAPEUTICS},
  number={ARTN 2300102},
  year = "2023"
}

BibTeX

@article{thermosensitive-2022/7,
  title={Thermosensitive liposomes: A promising step towards locsalised chemotherapy},
  author={Chaudhry M, Lyon P, Coussios C & Carlisle R},
  journal={Expert Opinion on Drug Delivery},
  publisher={Informa UK Limited},
  year = "2022"
}

BibTeX

@article{optimizationofc-2022/4,
  title={Optimization of cavitation-mediated mRNA delivery to cancer and non-cancer cells in vitro and in vivo},
  author={Martin A, Smith C, Carlisle R, Cleveland RO & Coussios C},
  journal={The Journal of the Acoustical Society of America},
  volume={151},
  pages={a80-a80},
  publisher={Acoustical Society of America (ASA)},
  year = "2022"
}

BibTeX

@article{bromopyruvateme-2021/10,
  title={3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation },
  author={Skaripa-Koukelli I, Hauton D, Walsby-Tickle J, Thomas E, Owen J et al.},
  journal={Cancer and Metabolism},
  volume={9},
  number={37},
  publisher={BioMed Central},
  year = "2021"
}

BibTeX

@article{gasstabilizings-2021/10,
  title={Gas-stabilizing solid cavitation nuclei for systemic or transdermal ultrasound-enhanced drug and vaccine delivery and immunomodulation},
  author={Lyons B, Hettinga J, Balkaran J, Collins A, Maardalen M et al.},
  journal={The Journal of the Acoustical Society of America},
  volume={150},
  pages={a54-a54},
  publisher={Acoustical Society of America (ASA)},
  year = "2021"
}

BibTeX

@article{expandingtheche-2021/8,
  title={Expanding the chemical functionality of DNA nanomaterials generated by rolling circle amplification},
  author={Baker YR, Yuan L, Chen J, Belle R, Carlisle R et al.},
  journal={Nucleic Acids Research},
  volume={49},
  pages={9042-9052},
  publisher={Oxford University Press},
  year = "2021"
}

BibTeX

@article{oligonucleotide-2021/8,
  title={Oligonucleotide-functionalized gold nanoparticles for synchronous telomerase inhibition, radiosensitization, and delivery of theranostic radionuclides},
  author={Bavelaar BM, Song L, Jackson MR, Able S, Tietz O et al.},
  journal={Molecular Pharmaceutics},
  volume={18},
  pages={3820-3831},
  publisher={American Chemical Society},
  year = "2021"
}

BibTeX

@article{abstractpredict-2021/7,
  title={Abstract 1369: Predicting clinical pharmacokinetics and toxicity of current and emerging oncology therapeutics by normothermic perfusion of isolated human-sized organs},
  author={Clark T, Bau L, Dengu F, Voyce D, Carlisle R et al.},
  journal={Cancer Research},
  volume={81},
  pages={1369-1369},
  publisher={American Association for Cancer Research (AACR)},
  year = "2021"
}

BibTeX

@article{polymerstealthi-2021/3,
  title={Polymer stealthing and mucin-1 retargeting for enhanced pharmacokinetics of an oncolytic vaccinia virus},
  author={Hill C, Grundy M, Bau L, Wallington S, Balkaran J et al.},
  journal={Molecular Therapy - Oncolytics},
  volume={21},
  pages={47-61},
  publisher={Cell Press},
  year = "2021"
}

BibTeX

@article{insituevaluatio-2021/2,
  title={In situ evaluation of spatiotemporal distribution of doxorubicin from Drug-eluting Beads in a tissue mimicking phantom},
  author={Caine M, Bian S, Tang Y, Garcia P, Henman A et al.},
  journal={European Journal of Pharmaceutical Sciences},
  volume={160},
  number={105772},
  publisher={Elsevier},
  year = "2021"
}

BibTeX

@article{quantifyingcell-2021/2,
  title={Quantifying cell death induced by doxorubicin, hyperthermia or HIFU ablation with flow cytometry},
  author={Lyon P, Suomi V, Jakeman P, Campo L, Coussios C et al.},
  journal={Scientific Reports},
  volume={11},
  number={4404},
  publisher={Springer Nature},
  year = "2021"
}

BibTeX

@article{improvedtherape-2021/1,
  title={Improved therapeutic antibody delivery to xenograft tumors using cavitation nucleated by gas-entrapping nanoparticles},
  author={Grundy M, Bau L, Hill C, Paverd C, Mannaris C et al.},
  journal={Nanomedicine },
  volume={16},
  pages={37-50},
  publisher={Future Medicine},
  year = "2021"
}

BibTeX

@article{largevolumehype-2021/1,
  title={Large-volume hyperthermia for safe and cost-effective targeted drug delivery using a clinical ultrasound-guided focused ultrasound device},
  author={Lyon PC, Mannaris C, Gray M, Carlisle R, Gleeson FV et al.},
  journal={Ultrasound in Medicine and Biology},
  volume={47},
  pages={982-997},
  publisher={Elsevier},
  year = "2021"
}

BibTeX

@article{vaccinationinto-2020/9,
  title={Vaccination into the Dermal Compartment: Techniques, Challenges, and Prospects.},
  author={Hettinga J & Carlisle R},
  journal={Vaccines},
  volume={8},
  pages={E534},
  year = "2020"
}

BibTeX

@article{aliposomebasedc-2020/7,
  title={A liposome-based cancer vaccine for a rapid and high-titre anti-ErbB-2 antibody response},
  author={Wallis J, Katti P, Martin AM, Hills T, Seymour LW et al.},
  journal={European Journal of Pharmaceutical Sciences},
  volume={152},
  number={105456},
  publisher={Elsevier},
  year = "2020"
}

BibTeX

@misc{methodsformodif-2020/1,
  title={Methods for Modification of Therapeutic Viruses.},
  author={Hill CAP, Bau L & Carlisle R},
  year = "2020"
}

BibTeX

@article{megavoltageradi-2020/1,
  title={Megavoltage radiosensitization of gold nanoparticles on a Glioblastoma Cancer Cell Line using a clinical platform},
  author={Kazmi F, Vallis K, Vellayappan BA, Bandla A, Yukun D et al.},
  journal={International Journal of Molecular Sciences},
  volume={21},
  number={429},
  publisher={MDPI},
  year = "2020"
}

@misc{dataforowenetal-2020/1,
  title={Data for Owen et al 2020 Journal controlled release},
  author={Carlisle RC},
  year = "2020"
}

BibTeX

@misc{expandingtheche-2020/,
  title={Expanding the Chemical Repertoire of DNA Nanomaterials Generated by Rolling Circle Amplification},
  author={Baker Y, Yuan L, Chen J, Belle R, Carlisle R et al.},
  year = "2020"
}

BibTeX

@article{indiumlabelling-2019/12,
  title={Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation},
  author={Owen J, Thomas E, Menon J, Gray M, Skaripa-Koukelli I et al.},
  journal={Journal of Controlled Release},
  volume={319},
  pages={222-233},
  publisher={Elsevier},
  year = "2019"
}

BibTeX

@article{megavoltageradi-2019/10,
  title={Megavoltage Radiosensitization of Gold Nanoparticles on Glioblastoma Cancer Cell Line Using a Clinical Platform},
  author={Kazmi F, Vallis KATHERINE, Vellayappan B, Bandla A, Yukun D et al.},
  journal={Preprints 2019},
  year = "2019"
}

BibTeX

@article{applicationsmec-2019/10,
  title={Applications, mechanisms and real-time monitoring of enhanced drug transport by sustained inertial cavitation},
  author={Smith C, Mannaris C, Katti P, Paverd C, Coviello C et al.},
  journal={The Journal of the Acoustical Society of America},
  volume={146},
  pages={2991-2991},
  publisher={Acoustical Society of America (ASA)},
  year = "2019"
}

BibTeX

@article{horsesforcourse-2019/10,
  title={Horses for courses (or something much smaller!): The design, development and acoustic testing of sub-micron cavitation nucleation agents for biomedical applications},
  author={Mannaris C, Bau L, Kwan JJ, Teo B, Gray M et al.},
  journal={The Journal of the Acoustical Society of America},
  volume={146},
  pages={2751-2751},
  publisher={Acoustical Society of America (ASA)},
  year = "2019"
}

BibTeX

@article{resultsoffirsti-2019/10,
  title={Results of first-in-man proof of concept study of ultrasound-triggered drug delivery in liver tumours},
  author={Lyon PC, Gray M, Mannaris C, Folkes L, Stratford M et al.},
  journal={Clinical Radiology},
  volume={74},
  pages={e20},
  publisher={Elsevier},
  year = "2019"
}

BibTeX

@article{ultrasoundmedia-2019/7,
  title={Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy},
  author={Thomas E, Menon JU, Owen J, Skaripa-Koukelli I, Wallington S et al.},
  journal={Theranostics},
  volume={9},
  pages={5595-5609},
  publisher={Ivyspring International Publisher},
  year = "2019"
}

BibTeX

@inproceedings{abstractcombini-2019/7,
  title={Abstract 994: Combining ruthenium metallo-intercalators and targeted radionuclide therapy for EGFR-overexpressing oesophageal cancer},
  author={Gill MR, Menon JU, Carlisle R & Vallis KA},
  booktitle={Cancer Chemistry},
  pages={994-994},
  year = "2019"
}

BibTeX

@article{achievingsystem-2019/5,
  title={Achieving systemic delivery of oncolytic viruses},
  author={Hill C & Carlisle R},
  journal={Expert Opinion on Drug Delivery},
  volume={16},
  pages={607-620},
  publisher={Taylor and Francis},
  year = "2019"
}

BibTeX

@article{novelapproaches-2019/4,
  title={Novel approaches for the design, delivery and administration of vaccine technologies},
  author={Wallis J, Shenton DP & Carlisle R},
  journal={Clinical and Experimental Immunology},
  volume={196},
  pages={189-204},
  year = "2019"
}

BibTeX

@article{microbubblesnan-2019/1,
  title={Microbubbles, nanodroplets and gas-stabilizing solid particles for ultrasound-mediated extravasation of unencapsulated drugs: an exposure parameter optimization study.},
  author={Mannaris C, Bau L, Grundy M, Gray M, Lea-Banks H et al.},
  journal={Ultrasound in Medicine and Biology},
  volume={45},
  pages={954-967},
  publisher={Elsevier},
  year = "2019"
}

BibTeX

@article{focusedultrasou-2019/1,
  title={Focused Ultrasound Hyperthermia for Targeted Drug Release from Thermosensitive Liposomes: Results from a Phase I Trial.},
  author={Lyon PC, Mannaris C, Folkes LK, Stratford M, Campo L et al.},
  journal={Radiology},
  year = "2019"
}

BibTeX

@article{focusedultrasou-2019/1,
  title={Focused ultrasound hyperthermia for targeted drug release from thermosensitive liposomes: results from a phase I trial},
  author={Gray MD, Lyon P, Mannaris C, Folkes L, Stratford M et al.},
  journal={Radiology},
  volume={291},
  pages={232-238},
  publisher={Radiological Society of North America},
  year = "2019"
}

@inproceedings{ultrasoundinduc-2019/,
  title={Ultrasound-Induced Mircobubble Cavitation For Optimisation Of Tumour Uptake Of Liposome-Based Chemo-Radionuclide Therapy},
  author={Vallis KA, Thomas E, Menon J, Owen J, Wallington S et al.},
  pages={S107-S108},
  year = "2019"
}

BibTeX

@article{longtermradiolo-2018/9,
  title={Long-term radiological and histological outcomes following selective internal radiation therapy to liver metastases from breast cancer},
  author={Lyon P, Winter H, Herbschleb K, Campo L, Carlisle R et al.},
  journal={Radiology Case Reports},
  volume={13},
  pages={1259-1266},
  publisher={Elsevier},
  year = "2018"
}

BibTeX

@article{safetyandfeasib-2018/7,
  title={Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial},
  author={Lyon P, Gray , Mannaris C, Folkes L, Stratford M et al.},
  journal={Lancet Oncology},
  volume={19},
  pages={1027-1039},
  publisher={Elsevier},
  year = "2018"
}

BibTeX

@article{poultrasoundtri-2018/6,
  title={PO-437 Ultrasound-triggered delivery of halogenated pyruvate analogues to breast cancer cells},
  author={Skaripa-Koukelli I, Owen J, Tietz O, Carlisle R & Vallis K},
  journal={ESMO Open},
  volume={3},
  pages={a194},
  publisher={Elsevier},
  year = "2018"
}

BibTeX

@article{inlabelledpolym-2018/5,
  title={111In-labelled polymeric nanoparticles incorporating a ruthenium-based radiosensitizer for EGFR-targeted combination therapy in oesophageal cancer cells},
  author={Gill MR, Menon JU, Jarman PJ, Owen J, Skaripa-Koukelli I et al.},
  journal={Nanoscale},
  volume={10},
  pages={10596-10608},
  publisher={Royal Society of Chemistry},
  year = "2018"
}

BibTeX

@article{passiveacoustic-2018/3,
  title={Passive acoustic mapping and B-mode ultrasound imaging utilizing compressed sensing for real-time monitoring of cavitation-enhanced drug delivery},
  author={Crake C, Finn S, Marsac L, Gray M, Carlisle R et al.},
  journal={The Journal of the Acoustical Society of America},
  volume={143},
  pages={1872-1872},
  publisher={Acoustical Society of America (ASA)},
  year = "2018"
}

BibTeX

@article{ultrasoundmedia-2018/1,
  title={Ultrasound-mediated cavitation does not decrease the activity of small molecule, antibody or viral-based medicines},
  author={Myers R, Grundy M, Rowe C, Coviello CM, Bau L et al.},
  journal={International Journal of Nanomedicine},
  volume={13},
  pages={337-349},
  publisher={Dove Medical Press},
  year = "2018"
}

BibTeX

@article{ultrasoundmedia-2017/12,
  title={Ultrasound-mediated cavitation-enhanced extravasation of mesoporous silica nanoparticles for controlled-release drug delivery},
  author={Paris JL, Mannaris C, Victoria Cabanas M, Carlisle R, Manzano M et al.},
  journal={Chemical Engineering Journal},
  volume={340},
  pages={2-8},
  publisher={Elsevier},
  year = "2017"
}

BibTeX

@article{clinicaltrialpr-2017/11,
  title={Clinical trial protocol for TARDOX: a phase I study to investigate the feasibility of targeted release of lyso-thermosensitive liposomal doxorubicin (ThermoDox®) using focused ultrasound in patients with liver tumours.},
  author={Lyon PC, Griffiths LF, Lee J, Chung D, Carlisle R et al.},
  journal={Journal of Therapeutic Ultrasound},
  volume={5},
  pages={28-28},
  year = "2017"
}

BibTeX

@article{alternativevacc-2017/8,
  title={Alternative vaccine administration by powder injection: Needle-free dermal delivery of the glycoconjugate meningococcal group Y vaccine},
  author={Weissmueller NT, Marsay L, Schiffter HA, Carlisle RC, Rollier CS et al.},
  journal={PLoS ONE},
  volume={12},
  number={e0183427},
  publisher={Public Library of Science},
  year = "2017"
}

BibTeX

@article{cavitationenhan-2017/5,
  title={Cavitation enhanced drug delivery in-vivo using combined B-mode guidance and real-time passive acoustic mapping: Challenges and results},
  author={Coviello C, Myers R, Jackson E, Lyka E, Morris L et al.},
  journal={The Journal of the Acoustical Society of America},
  volume={141},
  pages={3491-3491},
  publisher={Acoustical Society of America (ASA)},
  year = "2017"
}

BibTeX

@article{amultimodalinst-2017/3,
  title={A multimodal instrument for real-time in situ study of ultrasound and cavitation mediated drug delivery},
  author={Bian S, Seth A, Daly D, Carlisle R & Stride E},
  journal={Review of Scientific Instruments},
  volume={88},
  pages={034302},
  publisher={AIP Publishing},
  year = "2017"
}