Publications

BibTeX

@article{defattingofdono-2024/6,
  title={Defatting of donor transplant livers during normothermic perfusion - a randomised clinical trial: study protocol for the DeFat study},
  author={Abbas SH, Coussios C-C, Kounali D, Knight S & Friend P},
  journal={Trials},
  volume={25},
  number={386},
  publisher={BioMed Central},
  year = "2024"
}

BibTeX

@article{oimpairedoxygen-2024/3,
  title={O132: Impaired oxygen unloading from stored blood results in diffusion-limited oxygen release at tissues: evidence from twinned-circuit human kidney perfusion},
  author={Dumbill R, Rabcuka J, Fallon J, Knight S, Hunter J et al.},
  journal={British Journal of Surgery},
  volume={111},
  pages={znae046.014},
  publisher={Oxford University Press (OUP)},
  year = "2024"
}

BibTeX

@article{impairedounload-2023/12,
  title={Impaired O2 unloading from stored blood results in diffusion-limited O2 release at tissues: evidence from human kidneys},
  author={Dumbill R, Rabcuka J, Fallon J, Knight S, Hunter J et al.},
  journal={Blood},
  publisher={American Society of Hematology},
  year = "2023"
}

BibTeX

@article{normothermicmac-2023/11,
  title={Normothermic Machine Perfusion of Donor Livers for Transplantation in the United States: A Randomized Controlled Trial.},
  author={Chapman WC, Barbas AS, D'Alessandro AM, Vianna R, Kubal CA et al.},
  journal={Annals of surgery},
  volume={278},
  pages={e912-e921},
  year = "2023"
}

BibTeX

@article{hpbpexvivonormo-2023/11,
  title={HPB P26 Ex vivo normothermic perfusion of liver, kidney and spleen to predict human pharmacokinetics and assess drug delivery},
  author={Clark T, Bau L, Dengu F, Voyce D, Friend P et al.},
  journal={British Journal of Surgery},
  volume={110},
  publisher={Oxford University Press},
  year = "2023"
}

BibTeX

@article{sonosensitiveca-2023/11,
  title={Sonosensitive cavitation nuclei-a customisable platform technology for enhanced therapeutic delivery},
  author={Lyons B, Balkaran JPR, Dunn-Lawless D, Lucian V, Keller SB et al.},
  journal={Molecules},
  volume={28},
  number={7733},
  publisher={MDPI},
  year = "2023"
}

BibTeX

@article{investigationof-2023/10,
  title={Investigation of spatio-temporal inertial cavitation activity for optimization of needle-free ultrasound-enhanced vaccine delivery},
  author={Dunn-Lawless D, Balkaran J, Lyons B, Carlisle R, Coussios C et al.},
  journal={The Journal of the Acoustical Society of America},
  volume={154},
  pages={a24-a24},
  publisher={Acoustical Society of America (ASA)},
  year = "2023"
}

BibTeX

@article{clinicaltrialpr-2023/9,
  title={Clinical trial protocol for PanDox: a phase I study of targeted chemotherapy delivery to non-resectable primary pancreatic tumours using thermosensitive liposomal doxorubicin (ThermoDox®) and focused ultrasound},
  author={Spiers L, Gray M, Lyon P, Sivakumar S, Bekkali N et al.},
  journal={BMC Cancer},
  volume={23},
  number={896},
  publisher={BioMed Central},
  year = "2023"
}

BibTeX

@article{cavitationmedia-2023/9,
  title={Cavitation-mediated transcutaneous delivery of protein and nucleotide-based antigen for rapid high-level immune responses},
  author={Hettinga JK, Lyons B, Balkaran J, Rijal P, Dunn‐Lawless D et al.},
  journal={Advanced Therapeutics},
  volume={6},
  number={2300102},
  publisher={Wiley},
  year = "2023"
}

BibTeX

@article{cavitationmedia-2023/8,
  title={Cavitation-mediated immunomodulation and its use with checkpoint inhibitors},
  author={Maardalen M, Carlisle R & Coussios C},
  journal={Pharmaceutics},
  volume={15},
  number={2110},
  publisher={MDPI},
  year = "2023"
}

BibTeX

@article{cavitationmedia-2023/8,
  title={Cavitation-Mediated Immunomodulation and Its Use with Checkpoint Inhibitors.},
  author={Maardalen M, Carlisle R & Coussios C},
  journal={Pharmaceutics},
  volume={15},
  pages={2110},
  year = "2023"
}

BibTeX

@article{soundspeedandat-2023/7,
  title={Sound speed and attenuation of human pancreas and pancreatic tumors and their influence on focused ultrasound thermal and mechanical therapies},
  author={Gray MD, Spiers L & Coussios CC},
  journal={Medical Physics},
  volume={51},
  pages={809-825},
  publisher={Wiley},
  year = "2023"
}

BibTeX

@inproceedings{pamnotspamtowar-2023/3,
  title={PAM, not spam: Towards quantitative, reproducible, and energy-preserving cavitation imaging},
  author={Smith C, Bau L, Gray M & Coussios C},
  pages={a268-a268},
  year = "2023"
}

BibTeX

@inproceedings{desperatetimesc-2023/3,
  title={Desperate times call for disparate measures: Towards harmonization of cavitation data across environments and systems},
  author={Gray M & Coussios C},
  pages={a267-a267},
  year = "2023"
}

BibTeX

@inproceedings{hpbopreclinical-2022/12,
  title={HPB O03 Preclinical safety and feasibility of in situ Isolated Normothermic Liver Chemoperfusion (INLiC) for enhanced drug delivery},
  author={Clark T, Ebeling G, Bau L, Voyce D, Coussios C et al.},
  pages={znac404.017},
  year = "2022"
}

BibTeX

@misc{spatiotemporale-2022/10,
  title={Spatio-temporal evaluation of anti-biofilm cavitation activity by passive acoustic mapping},
  author={Keller S, LuTheryn G, Gray M, Stride EP, Cleveland RO et al.},
  year = "2022"
}

BibTeX

@article{paxpassiveactiv-2022/9,
  title={PAX (Passive-Active Crossing) method for sub-millimeter coregistration of passive acoustic mapping and b-mode images},
  author={Gray MD & Coussios CC},
  journal={IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control},
  volume={69},
  pages={3179-3189},
  publisher={IEEE},
  year = "2022"
}

BibTeX

@article{effectsofhumant-2022/7,
  title={Effects of human tissue acoustic properties, abdominal wall shape, and respiratory motion on ultrasound-mediated hyperthermia for targeted drug delivery to pancreatic tumors},
  author={Gray M, Spiers L & Coussios C},
  journal={International Journal of Hyperthermia},
  volume={39},
  pages={918-934},
  publisher={ Taylor and Francis Group},
  year = "2022"
}

BibTeX

@article{thermosensitive-2022/7,
  title={Thermosensitive liposomes: a promising step toward localised chemotherapy},
  author={Chaudhry M, Lyon P, Coussios C & Carlisle R},
  journal={Expert Opinion on Drug Delivery},
  volume={19},
  pages={899-912},
  publisher={Taylor and Francis Group},
  year = "2022"
}

BibTeX

@article{optimizationofc-2022/4,
  title={Optimization of cavitation-mediated mRNA delivery to cancer and non-cancer cells in vitro and in vivo},
  author={Martin A, Smith C, Carlisle R, Cleveland RO & Coussios C},
  journal={The Journal of the Acoustical Society of America},
  volume={151},
  pages={a80-a80},
  publisher={Acoustical Society of America (ASA)},
  year = "2022"
}

BibTeX

@misc{correlatinghigh-2022/4,
  title={Correlating high-speed optical imaging and passive acoustic mapping of cavitation dynamics},
  author={Wu Q, Gray M, Smith C, Bau L, Coussios C et al.},
  year = "2022"
}

BibTeX

@article{hemodynamicsand-2022/1,
  title={Hemodynamics and metabolic parameters in normothermic kidney preservation are linked with donor factors, perfusate cells, and cytokines},
  author={Weissenbacher A, Stone JP, Lo Faro ML, Hunter JP, Ploeg RJ et al.},
  journal={Frontiers in Medicine},
  volume={8},
  number={801098},
  publisher={Frontiers Media},
  year = "2022"
}

BibTeX

@article{preclinicalsafe-2022/1,
  title={Preclinical safety and feasibility of in situ Isolated Normothermic Liver Chemoperfusion (INLiC)},
  author={Clark T, Ebeling G, Baù L, Voyce D, Ogbemudia A et al.},
  journal={European Journal of Surgical Oncology},
  volume={48},
  pages={e4},
  publisher={Elsevier},
  year = "2022"
}

BibTeX

@article{gasstabilizings-2021/10,
  title={Gas-stabilizing solid cavitation nuclei for systemic or transdermal ultrasound-enhanced drug and vaccine delivery and immunomodulation},
  author={Lyons B, Hettinga J, Balkaran J, Collins A, Maardalen M et al.},
  journal={The Journal of the Acoustical Society of America},
  volume={150},
  pages={a54-a54},
  publisher={Acoustical Society of America (ASA)},
  year = "2021"
}

BibTeX

@article{epthpreclinical-2021/10,
  title={EP.TH.494Preclinical feasibility of in situ isolated normothermic liver chemoperfusion},
  author={Clark T, Ebeling G, Voyce D, Bau L, Coussios C et al.},
  journal={British Journal of Surgery},
  volume={108},
  pages={znab309.056},
  publisher={Oxford University Press (OUP)},
  year = "2021"
}

BibTeX

@article{noninvasiveasse-2021/7,
  title={Noninvasive assessment of steatosis and viability of cold-stored human liver grafts by MRI},
  author={Young L, Ceresa CDL, Mózes FE, Ellis J, Valkovič L et al.},
  journal={Magnetic Resonance in Medicine},
  volume={86},
  pages={3246-3258},
  publisher={Wiley},
  year = "2021"
}

BibTeX

@article{abstractpredict-2021/7,
  title={Abstract 1369: Predicting clinical pharmacokinetics and toxicity of current and emerging oncology therapeutics by normothermic perfusion of isolated human-sized organs},
  author={Clark T, Bau L, Dengu F, Voyce D, Carlisle R et al.},
  journal={Cancer Research},
  volume={81},
  pages={1369-1369},
  publisher={American Association for Cancer Research (AACR)},
  year = "2021"
}

BibTeX

@article{polymerstealthi-2021/3,
  title={Polymer stealthing and mucin-1 retargeting for enhanced pharmacokinetics of an oncolytic vaccinia virus},
  author={Hill C, Grundy M, Bau L, Wallington S, Balkaran J et al.},
  journal={Molecular Therapy - Oncolytics},
  volume={21},
  pages={47-61},
  publisher={Cell Press},
  year = "2021"
}

BibTeX

@article{quantifyingcell-2021/2,
  title={Quantifying cell death induced by doxorubicin, hyperthermia or HIFU ablation with flow cytometry},
  author={Lyon P, Suomi V, Jakeman P, Campo L, Coussios C et al.},
  journal={Scientific Reports},
  volume={11},
  number={4404},
  publisher={Springer Nature},
  year = "2021"
}

BibTeX

@article{largevolumehype-2021/1,
  title={Large-volume hyperthermia for safe and cost-effective targeted drug delivery using a clinical ultrasound-guided focused ultrasound device},
  author={Lyon PC, Mannaris C, Gray M, Carlisle R, Gleeson FV et al.},
  journal={Ultrasound in Medicine and Biology},
  volume={47},
  pages={982-997},
  publisher={Elsevier},
  year = "2021"
}

BibTeX

@article{improvedtherape-2021/1,
  title={Improved therapeutic antibody delivery to xenograft tumors using cavitation nucleated by gas-entrapping nanoparticles},
  author={Grundy M, Bau L, Hill C, Paverd C, Mannaris C et al.},
  journal={Nanomedicine },
  volume={16},
  pages={37-50},
  publisher={Future Medicine},
  year = "2021"
}

@inproceedings{preclinicalfeas-2021/,
  title={Preclinical feasibility of in situ isolated normothermic liver chemoperfusion},
  author={Clark T, Ebeling G, Voyce D, Bau L, Coussios C et al.},
  pages={166-166},
  year = "2021"
}

@inproceedings{predictingclini-2021/,
  title={Predicting clinical pharmacokinetics and toxicity of current and emerging oncology therapeutics by normothermic perfusion of isolated human-sized organs.},
  author={Clark T, Bau L, Dengu F, Voyce D, Carlisle R et al.},
  year = "2021"
}

BibTeX

@article{urinerecirculat-2020/10,
  title={Urine recirculation prolongs normothermic kidney perfusion via more optimal metabolic homeostasis – a proteomics study},
  author={Weissenbacher A, Huang H, Surik T, Lo Faro ML, Ploeg RJ et al.},
  journal={American Journal of Transplantation},
  number={ajt.16334},
  publisher={Wiley},
  year = "2020"
}

BibTeX

@article{weightforitadap-2020/10,
  title={Weight for it… adaptive beamformers in passive acoustic mapping for cavitation imaging},
  author={Gray M, Coviello C, Gyongy M, Lyka E, Paverd C et al.},
  journal={The Journal of the Acoustical Society of America},
  volume={148},
  pages={2449-2449},
  publisher={Acoustical Society of America (ASA)},
  year = "2020"
}

BibTeX

@article{dualarraypassiv-2020/8,
  title={Dual array passive acoustic mapping for cavitation imaging with enhanced 2-D resolution},
  author={Gray M, Elbes D, Paverd C, Lyka E, Coviello C et al.},
  journal={IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control},
  volume={68},
  pages={647-663},
  publisher={Institute of Electrical and Electronics Engineers},
  year = "2020"
}

BibTeX

@article{urinerecirculat-2020/3,
  title={Urine recirculation improves hemodynamics and enhances function in normothermic kidney perfusion },
  author={Weissenbacher A, Voyce D, Ceresa CDL, Soares MF, Roberts IS et al.},
  journal={Transplantation direct},
  volume={6},
  pages={e541},
  publisher={Lippincott, Williams & Wilkins},
  year = "2020"
}

BibTeX

@article{spatiotemporala-2020/2,
  title={Spatiotemporal assessment of the cellular safety of cavitation-based therapies by passive acoustic mapping},
  author={Smith CAB & Coussios CC},
  journal={Ultrasound in Medicine and Biology},
  volume={46},
  pages={1235-1243},
  publisher={Elsevier},
  year = "2020"
}

@inproceedings{arterialflowlac-2020/,
  title={Arterial Flow, Lactate and NGAL as a Decision Making Trinity in Normothermic Kidney Preservation},
  author={Weissenbacher A, Lo Faro ML, Coussios CC & Friend PJ},
  pages={683-683},
  year = "2020"
}

BibTeX

@inproceedings{urinerecirculat-2020/,
  title={Urine Recirculation Improves Hemodynamics and Enhances Function in Normothermic Kidney Perfusion},
  author={Weissenbacher A, Voyce D, Ceresa CDL, Soares MF, Roberts IS et al.},
  pages={e541},
  year = "2020"
}

BibTeX

@misc{heterogeneousti-2019/12,
  title={Heterogeneous tissue characterization using ultrasound: a comparison of fractal analysis backscatter models on liver tumors},
  author={Al-Kadi OS, Chung DYF, Coussios CC & Noble JA},
  year = "2019"
}

BibTeX

@article{horsesforcourse-2019/10,
  title={Horses for courses (or something much smaller!): The design, development and acoustic testing of sub-micron cavitation nucleation agents for biomedical applications},
  author={Mannaris C, Bau L, Kwan JJ, Teo B, Gray M et al.},
  journal={The Journal of the Acoustical Society of America},
  volume={146},
  pages={2751-2751},
  publisher={Acoustical Society of America (ASA)},
  year = "2019"
}

BibTeX

@article{applicationsmec-2019/10,
  title={Applications, mechanisms and real-time monitoring of enhanced drug transport by sustained inertial cavitation},
  author={Smith C, Mannaris C, Katti P, Paverd C, Coviello C et al.},
  journal={The Journal of the Acoustical Society of America},
  volume={146},
  pages={2991-2991},
  publisher={Acoustical Society of America (ASA)},
  year = "2019"
}

BibTeX

@article{resultsoffirsti-2019/10,
  title={Results of first-in-man proof of concept study of ultrasound-triggered drug delivery in liver tumours},
  author={Lyon PC, Gray M, Mannaris C, Folkes L, Stratford M et al.},
  journal={Clinical Radiology},
  volume={74},
  pages={e20},
  publisher={Elsevier},
  year = "2019"
}

BibTeX

@article{defininganuclei-2019/10,
  title={Defining a nuclei-independent unified cavitation dose for the spatiotemporal quantification of cavitation-mediated bioeffects by passive acoustic mapping},
  author={Smith C & Coussios C},
  journal={The Journal of the Acoustical Society of America},
  volume={146},
  pages={2991-2991},
  publisher={Acoustical Society of America (ASA)},
  year = "2019"
}

BibTeX

@article{compensationofa-2019/7,
  title={Compensation of array lens effects for improved co-registration of passive acoustic mapping and B-mode images for cavitation monitoring.},
  author={Gray MD & Coussios CC},
  journal={The Journal of the Acoustical Society of America},
  volume={146},
  pages={EL78},
  year = "2019"
}

BibTeX

@article{nucleationmappi-2019/6,
  title={Nucleation, mapping and control of cavitation for drug delivery},
  author={Stride E & Coussios C},
  journal={Nature Reviews Physics},
  volume={1},
  pages={495-509},
  publisher={Springer Nature},
  year = "2019"
}

BibTeX

@article{transientcoldst-2019/6,
  title={Transient cold storage prior to normothermic liver perfusion may facilitate adoption of a novel technology},
  author={Ceresa C, Nasralla D, Watson CJE, Butler AJ, Coussios CC et al.},
  journal={Liver Transplantation},
  volume={25},
  pages={1503-1513},
  publisher={Wiley},
  year = "2019"
}

BibTeX

@article{deliveringfocus-2019/5,
  title={Delivering focused ultrasound to intervertebral discs using time-reversal},
  author={Qiao S, Elbes D, Boubriak O, Urban J, Coussios C-C et al.},
  journal={Ultrasound in Medicine and Biology},
  volume={45},
  pages={2405-2416},
  publisher={Elsevier},
  year = "2019"
}

BibTeX

@article{sonothrombolysi-2019/2,
  title={Sonothrombolysis with magnetically targeted microbubbles},
  author={de Saint Victor M, Barnsley L, Carugo D, Owen J, Coussios C et al.},
  journal={Ultrasound in Medicine and Biology},
  volume={45},
  pages={1151-1163},
  publisher={Elsevier},
  year = "2019"
}