Showing 39 publications by Harrison Steel
Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system
Della Valle S, Steel H & Huang W (2025), Trends in Biotechnology
BibTeX
@article{streamlinedande-2025/3,
title={Streamlined and efficient genome editing in Cupriavidus necator H16 using an optimised SIBR-Cas system},
author={Della Valle S, Steel H & Huang W},
journal={Trends in Biotechnology},
publisher={Cell Press},
year = "2025"
}
Directing microbial co-culture composition using cybernetic control.
Lee TA, Morlock J, Allan J & Steel H (2025), Cell reports methods, 5(3), 101009
BibTeX
@article{directingmicrob-2025/3,
title={Directing microbial co-culture composition using cybernetic control. },
author={Lee TA, Morlock J, Allan J & Steel H},
journal={Cell reports methods},
volume={5},
pages={101009},
year = "2025"
}
Model-guided gene circuit design for engineering genetically stable cell populations in diverse applications.
Sechkar K & Steel H (2025), Journal of the Royal Society, Interface, 22(223), 20240602
BibTeX
@article{modelguidedgene-2025/2,
title={Model-guided gene circuit design for engineering genetically stable cell populations in diverse applications.},
author={Sechkar K & Steel H},
journal={Journal of the Royal Society, Interface},
volume={22},
pages={20240602},
publisher={The Royal Society},
year = "2025"
}
Optimisation strategies for directed evolution without sequencing
James J, Towers S, Foerster J & Steel H (2024), PLoS Computational Biology, 20(12)
BibTeX
@article{optimisationstr-2024/12,
title={Optimisation strategies for directed evolution without sequencing},
author={James J, Towers S, Foerster J & Steel H},
journal={PLoS Computational Biology},
volume={20},
number={e1012695},
publisher={Public Library of Science},
year = "2024"
}
Computational Synthetic Biology Enabled through JAX: A Showcase.
Gallup O, Sechkar K, Towers S & Steel H (2024), ACS synthetic biology, 13(9), 3046-3050
BibTeX
@article{computationalsy-2024/9,
title={Computational Synthetic Biology Enabled through JAX: A Showcase.},
author={Gallup O, Sechkar K, Towers S & Steel H},
journal={ACS synthetic biology},
volume={13},
pages={3046-3050},
year = "2024"
}
Integration of pH Control into Chi.Bio Reactors and Demonstration with Small-Scale Enzymatic Poly(ethylene terephthalate) Hydrolysis.
Denton MCR, Murphy NP, Norton-Baker B, Lua M, Steel H et al. (2024), Biochemistry, 63(13), 1599-1607
BibTeX
@article{integrationofph-2024/7,
title={Integration of pH Control into Chi.Bio Reactors and Demonstration with Small-Scale Enzymatic Poly(ethylene terephthalate) Hydrolysis.},
author={Denton MCR, Murphy NP, Norton-Baker B, Lua M, Steel H et al.},
journal={Biochemistry},
volume={63},
pages={1599-1607},
year = "2024"
}
A coarse-grained bacterial cell model for resource-aware analysis and design of synthetic gene circuits
Sechkar K, Steel H, Perrino G & Stan G-B (2024), Nature Communications, 15(1)
BibTeX
@article{acoarsegrainedb-2024/3,
title={A coarse-grained bacterial cell model for resource-aware analysis and design of synthetic gene circuits},
author={Sechkar K, Steel H, Perrino G & Stan G-B},
journal={Nature Communications},
volume={15},
number={1981},
publisher={Springer Nature},
year = "2024"
}
Deciphering mechanisms of production of natural compounds using inducer-producer microbial consortia
Gasparek M, Steel H & Papachristodoulou A (2023), Biotechnol Advances, 64
BibTeX
@article{decipheringmech-2023/2,
title={Deciphering mechanisms of production of natural compounds using inducer-producer microbial consortia},
author={Gasparek M, Steel H & Papachristodoulou A},
journal={Biotechnol Advances},
volume={64},
number={108117},
publisher={Elsevier},
year = "2023"
}
Dichotomous feedback: a signal sequestration-based feedback mechanism for biocontroller design.
Sootla A, Delalez N, Alexis E, Norman A, Steel H et al. (2022), Journal of the Royal Society, Interface, 19(189), 20210737
BibTeX
@article{dichotomousfeed-2022/4,
title={Dichotomous feedback: a signal sequestration-based feedback mechanism for biocontroller design.},
author={Sootla A, Delalez N, Alexis E, Norman A, Steel H et al.},
journal={Journal of the Royal Society, Interface},
volume={19},
number={ARTN 20210737},
pages={20210737},
publisher={The Royal Society},
year = "2022"
}
OxVent: Design and evaluation of a rapidly-manufactured Covid-19 ventilator
Beale R, Rosendo JB, Bergeles C, Beverly A, Camporota L et al. (2022), eBioMedicine, 76
BibTeX
@article{oxventdesignand-2022/2,
title={OxVent: Design and evaluation of a rapidly-manufactured Covid-19 ventilator},
author={Beale R, Rosendo JB, Bergeles C, Beverly A, Camporota L et al.},
journal={eBioMedicine},
volume={76},
number={103868},
publisher={Elsevier},
year = "2022"
}
Cybergenetic control of microbial community composition.
Lee TA & Steel H (2022), Frontiers in bioengineering and biotechnology, 10, 957140
BibTeX
@article{cybergeneticcon-2022/1,
title={Cybergenetic control of microbial community composition.},
author={Lee TA & Steel H},
journal={Frontiers in bioengineering and biotechnology},
volume={10},
pages={957140},
year = "2022"
}
Cells and computers, better together.
Zillig L & Steel H (2021), Nature reviews. Microbiology, 19(10), 622
BibTeX
@article{cellsandcompute-2021/10,
title={Cells and computers, better together.},
author={Zillig L & Steel H},
journal={Nature reviews. Microbiology},
volume={19},
pages={622},
year = "2021"
}
Redesign of ultrasensitive and robust RecA gene circuit to sense DNA damage
Chen JZ, Lim B, Steel H, Song Y, Ji M et al. (2021), Microbial Biotechnology, 14(6), 2481-2496
BibTeX
@article{redesignofultra-2021/3,
title={Redesign of ultrasensitive and robust RecA gene circuit to sense DNA damage},
author={Chen JZ, Lim B, Steel H, Song Y, Ji M et al.},
journal={Microbial Biotechnology},
volume={14},
pages={2481-2496},
publisher={Wiley},
year = "2021"
}
Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis
Rutten PJ, Steel H, Hood GA, Ramachandran V, McMurtry L et al. (2021), PLoS Genetics, 17(2)
BibTeX
@article{multiplesensors-2021/2,
title={Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis},
author={Rutten PJ, Steel H, Hood GA, Ramachandran V, McMurtry L et al.},
journal={PLoS Genetics},
volume={17},
number={e1009099},
publisher={Public Library of Science},
year = "2021"
}
Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis
Rutten PJ, Steel H, Hood GA, Ramachandran VK, McMurtry L et al. (2021), PLOS Genetics, 17(2), e1009099-e1009099
BibTeX
@article{multiplesensors-2021/2,
title={Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis},
author={Rutten PJ, Steel H, Hood GA, Ramachandran VK, McMurtry L et al.},
journal={PLOS Genetics},
volume={17},
pages={e1009099-e1009099},
publisher={Public Library of Science (PLoS)},
year = "2021"
}
In situ characterisation and manipulation of biological systems with Chi.Bio - Design Files
Steel H & Papachristodoulou A (2020)
BibTeX
@misc{insitucharacter-2020/1,
title={In situ characterisation and manipulation of biological systems with Chi.Bio - Design Files},
author={Steel H & Papachristodoulou A},
year = "2020"
}
The effect of spatiotemporal antibiotic inhomogeneities on the evolution of resistance
Steel H & Papachristodoulou A (2019), Journal of Theoretical Biology, 486
BibTeX
@article{theeffectofspat-2019/11,
title={The effect of spatiotemporal antibiotic inhomogeneities on the evolution of resistance},
author={Steel H & Papachristodoulou A},
journal={Journal of Theoretical Biology},
volume={486},
number={110077},
publisher={Elsevier},
year = "2019"
}
Low-burden biological feedback controllers for near-perfect adaptation
Steel H & Papachristodoulou A (2019), ACS Synthetic Biology, 8(10), 2212-2219
BibTeX
@article{lowburdenbiolog-2019/9,
title={Low-burden biological feedback controllers for near-perfect adaptation},
author={Steel H & Papachristodoulou A},
journal={ACS Synthetic Biology},
volume={8},
pages={2212-2219},
publisher={American Chemical Society},
year = "2019"
}
Characterisation and development of aspirin inducible biosensors in E. coli and SimCells
Chen JX, Steel H, Wu Y-H, Wang Y, Xu J et al. (2019), Applied and Environmental Microbiology, 85(6), e02959-18
BibTeX
@article{characterisatio-2019/1,
title={Characterisation and development of aspirin inducible biosensors in E. coli and SimCells},
author={Chen JX, Steel H, Wu Y-H, Wang Y, Xu J et al.},
journal={Applied and Environmental Microbiology},
volume={85},
pages={e02959-18},
publisher={American Society for Microbiology},
year = "2019"
}
Chi.Bio: An open-source automated experimental platform for biological science research
Steel H, Habgood R, Kelly C & Papachristodoulou A (2019)
BibTeX
@article{chibioanopensou-2019/,
title={Chi.Bio: An open-source automated experimental platform for biological science research},
author={Steel H, Habgood R, Kelly C & Papachristodoulou A},
journal={},
year = "2019"
}
Improving orthogonality in two-component biological signalling systems using feedback control
Steel H, Sootla A, Smart B, Delalez N & Papachristodoulou A (2018), IEEE Control Systems Letters, 3(2), 326-331
BibTeX
@article{improvingorthog-2018/9,
title={Improving orthogonality in two-component biological signalling systems using feedback control},
author={Steel H, Sootla A, Smart B, Delalez N & Papachristodoulou A},
journal={IEEE Control Systems Letters},
volume={3},
pages={326-331},
publisher={IEEE},
year = "2018"
}
Synthetic negative feedback circuits using engineered small RNAs
Kelly C, Harris A, Steel H, Hancock E, Heap JT et al. (2018), Nucleic acids research, 46(18), 9875-9889
BibTeX
@article{syntheticnegati-2018/9,
title={Synthetic negative feedback circuits using engineered small RNAs},
author={Kelly C, Harris A, Steel H, Hancock E, Heap JT et al.},
journal={Nucleic acids research},
volume={46},
pages={9875-9889},
publisher={Oxford University Press},
year = "2018"
}
Probing intercell variability using bulk measurements
Steel H & Papachristodoulou A (2018), ACS Synthetic Biology, 7(6), 1528-1537
BibTeX
@article{probingintercel-2018/5,
title={Probing intercell variability using bulk measurements},
author={Steel H & Papachristodoulou A},
journal={ACS Synthetic Biology},
volume={7},
pages={1528-1537},
publisher={American Chemical Society},
year = "2018"
}
Design constraints for biological systems that achieve adaptation and disturbance rejection
Steel H & Papachristodoulou A (2018), IEEE Transactions on Control of Network Systems, 5(2), 807-817
BibTeX
@article{designconstrain-2018/1,
title={Design constraints for biological systems that achieve adaptation and disturbance rejection},
author={Steel H & Papachristodoulou A},
journal={IEEE Transactions on Control of Network Systems},
volume={5},
pages={807-817},
publisher={IEEE},
year = "2018"
}
The autorepressor: A case study of the importance of model selection
Harris AWK, Kelly CL, Steel H & Papachristodoulou A (2018), 56th IEEE Conference on Decision and Control (CDC 2017)
BibTeX
@inproceedings{theautorepresso-2018/1,
title={The autorepressor: A case study of the importance of model selection},
author={Harris AWK, Kelly CL, Steel H & Papachristodoulou A},
year = "2018"
}
Frequency domain analysis of small non-coding RNAs shows summing junction-like behaviour
Steel HCB, Harris AWK, Hancock EJ, Kelly CL & Papachristodoulou A (2018), 56th IEEE Conference on Decision and Control (CDC 2017)
BibTeX
@inproceedings{frequencydomain-2018/1,
title={Frequency domain analysis of small non-coding RNAs shows summing junction-like behaviour},
author={Steel HCB, Harris AWK, Hancock EJ, Kelly CL & Papachristodoulou A},
year = "2018"
}
Challenges at the interface of control engineering and synthetic biology
Steel H, Lillacci G, Khammash M & Papachristodoulou A (2018), 56th IEEE Conference on Decision and Control (CDC 2017)
BibTeX
@inproceedings{challengesatthe-2018/1,
title={Challenges at the interface of control engineering and synthetic biology},
author={Steel H, Lillacci G, Khammash M & Papachristodoulou A},
year = "2018"
}
Characterisation and development of aspirin inducible biosensors in<i>E. coli</i>Nissle 1917 and SimCells
Chen JX, Steel H, Wu Y-H, Wang Y, Xu J et al. (2018)
BibTeX
@misc{characterisatio-2018/,
title={Characterisation and development of aspirin inducible biosensors in<i>E. coli</i>Nissle 1917 and SimCells},
author={Chen JX, Steel H, Wu Y-H, Wang Y, Xu J et al.},
year = "2018"
}
Feedback Control and Synthetic Biology: Constraints on Design
Steel HCB & Papachristodoulou A (2017), IFAC-PapersOnLine, 50(1), 10932-10937
BibTeX
@article{feedbackcontrol-2017/10,
title={Feedback Control and Synthetic Biology: Constraints on Design},
author={Steel HCB & Papachristodoulou A},
journal={IFAC-PapersOnLine},
volume={50},
pages={10932-10937},
publisher={Elsevier},
year = "2017"
}
Ribo-attenuators: novel elements for reliable and modular riboswitch engineering
Folliard T, Mertins B, Steel H, Prescott TP, Newport T et al. (2017), Scientific Reports, 7
BibTeX
@article{riboattenuators-2017/7,
title={Ribo-attenuators: novel elements for reliable and modular riboswitch engineering},
author={Folliard T, Mertins B, Steel H, Prescott TP, Newport T et al.},
journal={Scientific Reports},
volume={7},
number={4599},
publisher={Springer Nature},
year = "2017"
}
A synthetic recombinase-based feedback loop results in robust expression.
Folliard T, Steel H, Prescott T, Wadhams G, Rothschild L et al. (2017), ACS Synthetic Biology
BibTeX
@article{asyntheticrecom-2017/6,
title={A synthetic recombinase-based feedback loop results in robust expression.},
author={Folliard T, Steel H, Prescott T, Wadhams G, Rothschild L et al.},
journal={ACS Synthetic Biology},
publisher={ACS Publications},
year = "2017"
}
Synthetic negative feedback circuits using engineered small RNAs
Kelly C, Harris A, Steel H, Hancock E, Heap J et al. (2017)
BibTeX
@misc{syntheticnegati-2017/,
title={Synthetic negative feedback circuits using engineered small RNAs},
author={Kelly C, Harris A, Steel H, Hancock E, Heap J et al.},
year = "2017"
}
The FLASHForward facility at DESY
Aschikhin A, Behrens C, Bohlen S, Dale J, Delbos N et al. (2015), Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 806, 175-183
BibTeX
@article{theflashforward-2015/10,
title={The FLASHForward facility at DESY},
author={Aschikhin A, Behrens C, Bohlen S, Dale J, Delbos N et al.},
journal={Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment},
volume={806},
pages={175-183},
publisher={Elsevier},
year = "2015"
}
Modeling circulation and seasonal fluctuations in perennially ice‐covered and ice‐walled Lake Untersee, Antarctica
Steel HCB, McKay CP & Andersen DT (2015), Limnology and Oceanography, 60(4), 1139-1155
BibTeX
@article{modelingcircula-2015/7,
title={Modeling circulation and seasonal fluctuations in perennially ice‐covered and ice‐walled Lake Untersee, Antarctica},
author={Steel HCB, McKay CP & Andersen DT},
journal={Limnology and Oceanography},
volume={60},
pages={1139-1155},
publisher={Wiley},
year = "2015"
}
The internal-external respiratory motion correlation is unaffected by audiovisual biofeedback.
Steel H, Pollock S, Lee D, Keall P & Kim T (2014), Australasian physical & engineering sciences in medicine, 37(1), 97-102
BibTeX
@article{theinternalexte-2014/3,
title={The internal-external respiratory motion correlation is unaffected by audiovisual biofeedback.},
author={Steel H, Pollock S, Lee D, Keall P & Kim T},
journal={Australasian physical & engineering sciences in medicine},
volume={37},
pages={97-102},
year = "2014"
}
The performance of field scientists undertaking observations of early life fossils while in simulated space suit
Willson D, Rask JC, George SC, de Leon P, Bonaccorsi R et al. (2014), Acta Astronautica, 93, 193-206
BibTeX
@article{theperformanceo-2014/1,
title={The performance of field scientists undertaking observations of early life fossils while in simulated space suit},
author={Willson D, Rask JC, George SC, de Leon P, Bonaccorsi R et al.},
journal={Acta Astronautica},
volume={93},
pages={193-206},
publisher={Elsevier},
year = "2014"
}
Dynamic patterns and their interactions in networks of excitable elements.
Gong P, Steel H, Robinson P & Qi Y (2013), Physical review. E, Statistical, nonlinear, and soft matter physics, 88(4), 042821
BibTeX
@article{dynamicpatterns-2013/10,
title={Dynamic patterns and their interactions in networks of excitable elements.},
author={Gong P, Steel H, Robinson P & Qi Y},
journal={Physical review. E, Statistical, nonlinear, and soft matter physics},
volume={88},
pages={042821},
year = "2013"
}
Mitigating Biological Signalling Cross-talk with Feedback Control
Steel H, Sootla A, Delalez N & Papachristodoulou A (0), 2638-2643
BibTeX
@inproceedings{mitigatingbiolo-/,
title={Mitigating Biological Signalling Cross-talk with Feedback Control},
author={Steel H, Sootla A, Delalez N & Papachristodoulou A},
booktitle={2019 18th European Control Conference (ECC)},
pages={2638-2643}
}
Optimisation strategies for directed evolution without sequencing
James J, Towers S, Foerster J & Steel H (0)
BibTeX
@misc{optimisationstr-/,
title={Optimisation strategies for directed evolution without sequencing},
author={James J, Towers S, Foerster J & Steel H}
}