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Showing 24 publications by Harrison Steel

A coarse-grained bacterial cell model for resource-aware analysis and design of synthetic gene circuits

Sechkar K, Steel H, Perrino G & Stan G-B (2024), Nature Communications, 15(1)

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@article{acoarsegrainedb-2024/3,
  title={A coarse-grained bacterial cell model for resource-aware analysis and design of synthetic gene circuits},
  author={Sechkar K, Steel H, Perrino G & Stan G-B},
  journal={Nature Communications},
  volume={15},
  number={1981},
  publisher={Springer Nature},
  year = "2024"
}

Deciphering mechanisms of production of natural compounds using inducer-producer microbial consortia

Gasparek M, Steel H & Papachristodoulou A (2023), Biotechnol Advances, 64

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@article{decipheringmech-2023/2,
  title={Deciphering mechanisms of production of natural compounds using inducer-producer microbial consortia},
  author={Gasparek M, Steel H & Papachristodoulou A},
  journal={Biotechnol Advances},
  volume={64},
  number={108117},
  publisher={Elsevier},
  year = "2023"
}

Cells and computers, better together.

Zillig L & Steel H (2021), Nature reviews. Microbiology, 19(10), 622

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@article{cellsandcompute-2021/10,
  title={Cells and computers, better together.},
  author={Zillig L & Steel H},
  journal={Nature reviews. Microbiology},
  volume={19},
  pages={622},
  year = "2021"
}

Redesign of ultrasensitive and robust RecA gene circuit to sense DNA damage

Chen JZ, Lim B, Steel H, Song Y, Ji M et al. (2021), Microbial Biotechnology, 14(6), 2481-2496

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@article{redesignofultra-2021/3,
  title={Redesign of ultrasensitive and robust RecA gene circuit to sense DNA damage},
  author={Chen JZ, Lim B, Steel H, Song Y, Ji M et al.},
  journal={Microbial Biotechnology},
  volume={14},
  pages={2481-2496},
  publisher={Wiley},
  year = "2021"
}

Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis

Rutten PJ, Steel H, Hood GA, Ramachandran V, McMurtry L et al. (2021), PLoS Genetics, 17(2)

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@article{multiplesensors-2021/2,
  title={Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis},
  author={Rutten PJ, Steel H, Hood GA, Ramachandran V, McMurtry L et al.},
  journal={PLoS Genetics},
  volume={17},
  number={e1009099},
  publisher={Public Library of Science},
  year = "2021"
}

Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis

Rutten PJ, Steel H, Hood GA, Ramachandran VK, McMurtry L et al. (2021), PLOS Genetics, 17(2), e1009099-e1009099

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@article{multiplesensors-2021/2,
  title={Multiple sensors provide spatiotemporal oxygen regulation of gene expression in a Rhizobium-legume symbiosis},
  author={Rutten PJ, Steel H, Hood GA, Ramachandran VK, McMurtry L et al.},
  journal={PLOS Genetics},
  volume={17},
  pages={e1009099-e1009099},
  publisher={Public Library of Science (PLoS)},
  year = "2021"
}

In situ characterisation and manipulation of biological systems with Chi.Bio - Design Files

Steel H & Papachristodoulou A (2020)

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@misc{insitucharacter-2020/1,
  title={In situ characterisation and manipulation of biological systems with Chi.Bio - Design Files},
  author={Steel H & Papachristodoulou A},
  year = "2020"
}

The effect of spatiotemporal antibiotic inhomogeneities on the evolution of resistance

Steel H & Papachristodoulou A (2019), Journal of Theoretical Biology, 486

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@article{theeffectofspat-2019/11,
  title={The effect of spatiotemporal antibiotic inhomogeneities on the evolution of resistance},
  author={Steel H & Papachristodoulou A},
  journal={Journal of Theoretical Biology},
  volume={486},
  number={110077},
  publisher={Elsevier},
  year = "2019"
}

Low-burden biological feedback controllers for near-perfect adaptation

Steel H & Papachristodoulou A (2019), ACS Synthetic Biology, 8(10), 2212-2219

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@article{lowburdenbiolog-2019/9,
  title={Low-burden biological feedback controllers for near-perfect adaptation},
  author={Steel H & Papachristodoulou A},
  journal={ACS Synthetic Biology},
  volume={8},
  pages={2212-2219},
  publisher={American Chemical Society},
  year = "2019"
}

Characterisation and development of aspirin inducible biosensors in E. coli and SimCells

Chen JX, Steel H, Wu Y-H, Wang Y, Xu J et al. (2019), Applied and Environmental Microbiology, 85(6), e02959-18

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@article{characterisatio-2019/1,
  title={Characterisation and development of aspirin inducible biosensors in E. coli and SimCells},
  author={Chen JX, Steel H, Wu Y-H, Wang Y, Xu J et al.},
  journal={Applied and Environmental Microbiology},
  volume={85},
  pages={e02959-18},
  publisher={American Society for Microbiology},
  year = "2019"
}

Chi.Bio: An open-source automated experimental platform for biological science research

Steel H, Habgood R, Kelly C & Papachristodoulou A (2019)

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@article{chibioanopensou-2019/,
  title={Chi.Bio: An open-source automated experimental platform for biological science research},
  author={Steel H, Habgood R, Kelly C & Papachristodoulou A},
  journal={},
  year = "2019"
}

Improving orthogonality in two-component biological signalling systems using feedback control

Steel H, Sootla A, Smart B, Delalez N & Papachristodoulou A (2018), IEEE Control Systems Letters, 3(2), 326-331

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@article{improvingorthog-2018/9,
  title={Improving orthogonality in two-component biological signalling systems using feedback control},
  author={Steel H, Sootla A, Smart B, Delalez N & Papachristodoulou A},
  journal={IEEE Control Systems Letters},
  volume={3},
  pages={326-331},
  publisher={IEEE},
  year = "2018"
}

Synthetic negative feedback circuits using engineered small RNAs

Kelly C, Harris A, Steel H, Hancock E, Heap JT et al. (2018), Nucleic acids research, 46(18), 9875-9889

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@article{syntheticnegati-2018/9,
  title={Synthetic negative feedback circuits using engineered small RNAs},
  author={Kelly C, Harris A, Steel H, Hancock E, Heap JT et al.},
  journal={Nucleic acids research},
  volume={46},
  pages={9875-9889},
  publisher={Oxford University Press},
  year = "2018"
}

Probing intercell variability using bulk measurements

Steel H & Papachristodoulou A (2018), ACS Synthetic Biology, 7(6), 1528-1537

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@article{probingintercel-2018/5,
  title={Probing intercell variability using bulk measurements},
  author={Steel H & Papachristodoulou A},
  journal={ACS Synthetic Biology},
  volume={7},
  pages={1528-1537},
  publisher={American Chemical Society},
  year = "2018"
}

Design constraints for biological systems that achieve adaptation and disturbance rejection

Steel H & Papachristodoulou A (2018), IEEE Transactions on Control of Network Systems, 5(2), 807-817

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@article{designconstrain-2018/1,
  title={Design constraints for biological systems that achieve adaptation and disturbance rejection},
  author={Steel H & Papachristodoulou A},
  journal={IEEE Transactions on Control of Network Systems},
  volume={5},
  pages={807-817},
  publisher={IEEE},
  year = "2018"
}

The autorepressor: A case study of the importance of model selection

Harris AWK, Kelly CL, Steel H & Papachristodoulou A (2018), 56th IEEE Conference on Decision and Control (CDC 2017)

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@inproceedings{theautorepresso-2018/1,
  title={The autorepressor: A case study of the importance of model selection},
  author={Harris AWK, Kelly CL, Steel H & Papachristodoulou A},
  year = "2018"
}

Frequency domain analysis of small non-coding RNAs shows summing junction-like behaviour

Steel HCB, Harris AWK, Hancock EJ, Kelly CL & Papachristodoulou A (2018), 56th IEEE Conference on Decision and Control (CDC 2017)

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@inproceedings{frequencydomain-2018/1,
  title={Frequency domain analysis of small non-coding RNAs shows summing junction-like behaviour},
  author={Steel HCB, Harris AWK, Hancock EJ, Kelly CL & Papachristodoulou A},
  year = "2018"
}

Challenges at the interface of control engineering and synthetic biology

Steel H, Lillacci G, Khammash M & Papachristodoulou A (2018), 56th IEEE Conference on Decision and Control (CDC 2017)

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@inproceedings{challengesatthe-2018/1,
  title={Challenges at the interface of control engineering and synthetic biology},
  author={Steel H, Lillacci G, Khammash M & Papachristodoulou A},
  year = "2018"
}

Characterisation and development of aspirin inducible biosensors in<i>E. coli</i>Nissle 1917 and SimCells

Chen JX, Steel H, Wu Y-H, Wang Y, Xu J et al. (2018)

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@misc{characterisatio-2018/,
  title={Characterisation and development of aspirin inducible biosensors in<i>E. coli</i>Nissle 1917 and SimCells},
  author={Chen JX, Steel H, Wu Y-H, Wang Y, Xu J et al.},
  year = "2018"
}

Feedback Control and Synthetic Biology: Constraints on Design

Steel HCB & Papachristodoulou A (2017), IFAC-PapersOnLine, 50(1), 10932-10937

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@article{feedbackcontrol-2017/10,
  title={Feedback Control and Synthetic Biology: Constraints on Design},
  author={Steel HCB & Papachristodoulou A},
  journal={IFAC-PapersOnLine},
  volume={50},
  pages={10932-10937},
  publisher={Elsevier},
  year = "2017"
}

A synthetic recombinase-based feedback loop results in robust expression.

Folliard T, Steel H, Prescott T, Wadhams G, Rothschild L et al. (2017), ACS Synthetic Biology

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@article{asyntheticrecom-2017/6,
  title={A synthetic recombinase-based feedback loop results in robust expression.},
  author={Folliard T, Steel H, Prescott T, Wadhams G, Rothschild L et al.},
  journal={ACS Synthetic Biology},
  publisher={ACS Publications},
  year = "2017"
}

Synthetic negative feedback circuits using engineered small RNAs

Kelly C, Harris A, Steel H, Hancock E, Heap J et al. (2017)

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@misc{syntheticnegati-2017/,
  title={Synthetic negative feedback circuits using engineered small RNAs},
  author={Kelly C, Harris A, Steel H, Hancock E, Heap J et al.},
  year = "2017"
}

Mitigating Biological Signalling Cross-talk with Feedback Control

Steel H, Sootla A, Delalez N & Papachristodoulou A (0), 2638-2643

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@inproceedings{mitigatingbiolo-/,
  title={Mitigating Biological Signalling Cross-talk with Feedback Control},
  author={Steel H, Sootla A, Delalez N & Papachristodoulou A},
  booktitle={2019 18th European Control Conference (ECC)},
  pages={2638-2643}
}

Optimisation strategies for directed evolution without sequencing

James J, Towers S, Foerster J & Steel H (0)

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@misc{optimisationstr-/,
  title={Optimisation strategies for directed evolution without sequencing},
  author={James J, Towers S, Foerster J & Steel H}
}