Showing 50 publications by Lei Clifton
Bridging the generalisation gap: synthetic data generation for multi-site clinical model validation
Segal B, Fieggen J, Clifton D & Clifton L (2025)
BibTeX
@inproceedings{bridgingthegene-2025/7,
title={Bridging the generalisation gap: synthetic data generation for multi-site clinical model validation},
author={Segal B, Fieggen J, Clifton D & Clifton L},
booktitle={47th Annual International Conference of the IEEE Engineering in Medicine and Biology Society},
year = "2025"
}
Implementation framework for AI deployment at scale in healthcare systems.
Adnan HS, Shidani A, Clifton L, Bankhead CR & Perera-Salazar R (2025), iScience, 28(5), 112406
Dysregulated immune proteins in plasma in the UK Biobank predict Multiple Myeloma 12 years before clinical diagnosis
Fieggen J, Thakur A, Butler CC, Ramasamy K, Thakurta A et al. (2025), Blood Advances
BibTeX
@article{dysregulatedimm-2025/5,
title={Dysregulated immune proteins in plasma in the UK Biobank predict Multiple Myeloma 12 years before clinical diagnosis},
author={Fieggen J, Thakur A, Butler CC, Ramasamy K, Thakurta A et al.},
journal={Blood Advances},
publisher={American Society of Hematology},
year = "2025"
}
Application of large language models in medicine
Liu F, Zhou H, Gu B, Zou X, Huang J et al. (2025), Nature Reviews Bioengineering
Bridging the Generalisation Gap: Synthetic Data Generation for Multi-Site Clinical Model Validation
Segal B, Fieggen J, Clifton D & Clifton L (2025)
RiskAgent: Autonomous Medical AI Copilot for Generalist Risk Prediction
Liu F, Wu J, Zhou H, Gu X, Molaei S et al. (2025)
Individualised Treatment Effects Estimation with Composite Treatments and Composite Outcomes
Chauhan VK, Clifton L, Nigam G & Clifton DA (2025)
Aligning, autoencoding and prompting large language models for novel disease reporting
Liu F, Wu X, Huang J, Yang B, Branson K et al. (2025), IEEE Transactions on Pattern Analysis and Machine Intelligence, 47(5), 3332-3343
BibTeX
@article{aligningautoenc-2025/1,
title={Aligning, autoencoding and prompting large language models for novel disease reporting},
author={Liu F, Wu X, Huang J, Yang B, Branson K et al.},
journal={IEEE Transactions on Pattern Analysis and Machine Intelligence},
volume={47},
pages={3332-3343},
publisher={IEEE},
year = "2025"
}
Refined matrix completion for spectrum estimation of heart rate variability
Lu L, Zhu T, Tan Y, Zhou J, Yang J et al. (2024), Mathematical Biosciences and Engineering, 21(8), 6758-6782
BibTeX
@article{refinedmatrixco-2024/8,
title={Refined matrix completion for spectrum estimation of heart rate variability},
author={Lu L, Zhu T, Tan Y, Zhou J, Yang J et al.},
journal={Mathematical Biosciences and Engineering},
volume={21},
pages={6758-6782},
publisher={AIMS Press},
year = "2024"
}
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods
Mesinovic M, Wong XC, Rajahram GS, Citarella BW, Peariasamy KM et al. (2024), Scientific Reports, 14(1)
BibTeX
@article{atadmissionpred-2024/7,
title={At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods},
author={Mesinovic M, Wong XC, Rajahram GS, Citarella BW, Peariasamy KM et al.},
journal={Scientific Reports},
volume={14},
number={16387},
publisher={Nature Research},
year = "2024"
}
Figure 3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Supplementary Table S2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S5 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S5 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Figure S3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryfi-2024/6,
title={Supplementary Figure S3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Figure S5 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryfi-2024/6,
title={Supplementary Figure S5 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Figure S2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryfi-2024/6,
title={Supplementary Figure S2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Figure S4 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryfi-2024/6,
title={Supplementary Figure S4 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Data from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Supplementary Table S7 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S7 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S9 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S9 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S9 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S9 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S7 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S7 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S6 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S6 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S8 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S8 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S5 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S5 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Figure S3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryfi-2024/6,
title={Supplementary Figure S3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Table 2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Supplementary Figure S1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryfi-2024/6,
title={Supplementary Figure S1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Figure 2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Figure 1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Supplementary Figure S5 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryfi-2024/6,
title={Supplementary Figure S5 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Figure S2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryfi-2024/6,
title={Supplementary Figure S2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Table 1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Figure 1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Supplementary Figure S4 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryfi-2024/6,
title={Supplementary Figure S4 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S4 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S4 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S6 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S6 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S4 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S4 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Table 1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Figure 2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Figure 3 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Table 2 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Data from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
Supplementary Figure S1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryfi-2024/6,
title={Supplementary Figure S1 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}
Supplementary Table S8 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank
Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al. (2024)
BibTeX
@misc{supplementaryta-2024/6,
title={Supplementary Table S8 from Assessing the Value of Incorporating a Polygenic Risk Score with Nongenetic Factors for Predicting Breast Cancer Diagnosis in the UK Biobank},
author={Collister JA, Liu X, Littlejohns TJ, Cuzick J, Clifton L et al.},
year = "2024"
}