Showing 150 publications by Ben Seymour
Why sleep matters in chronic pain: evidence across the lifespan
Kelleher EM, Wall A, Seymour B & Irani A (2026), EBioMedicine, 125, 106158
Homeostasis after injury: How intertwined inference and control underpin post-injury pain and behaviour.
Mahajan P, Dayan P & Seymour B (2026), PLOS Computational Biology, 22(1), e1013538
BibTeX
@article{homeostasisafte-2026/1,
title={Homeostasis after injury: How intertwined inference and control underpin post-injury pain and behaviour.},
author={Mahajan P, Dayan P & Seymour B},
journal={PLOS Computational Biology},
volume={22},
number={ARTN e1013538},
pages={e1013538},
publisher={Public Library of Science (PLoS)},
year = "2026"
}
Tonic pain modulates neural correlates of associative phasic pain memories.
Hewitt D, Tong S, Schreiber S & Seymour B (2026), Pain
Wirelessly transmitted subthalamic nucleus signals decode endogenous pain levels in Parkinson's disease patients
Reza A, Yanagisawa T, Tani N, Fukuma R, Emura T et al. (2025), Neurobiology of Disease, 107235
BibTeX
@article{wirelesslytrans-2025/12,
title={Wirelessly transmitted subthalamic nucleus signals decode endogenous pain levels in Parkinson's disease patients},
author={Reza A, Yanagisawa T, Tani N, Fukuma R, Emura T et al.},
journal={Neurobiology of Disease},
pages={107235},
publisher={Elsevier},
year = "2025"
}
Neural associative skill memories for safer robotics and modelling human sensorimotor repertoires
Mahajan P, Tang M, Li TE, Havoutis I & Seymour B (2025), Neural Computation, 38(1), 1-27
BibTeX
@article{neuralassociati-2025/11,
title={Neural associative skill memories for safer robotics and modelling human sensorimotor repertoires},
author={Mahajan P, Tang M, Li TE, Havoutis I & Seymour B},
journal={Neural Computation},
volume={38},
pages={1-27},
publisher={Massachusetts Institute of Technology Press},
year = "2025"
}
Forward and reverse engineering the pain system: from computational neuroscience to neuro-engineering.
Mahajan P & Seymour B (2025), Pain, 166(11S), S75-S78
The AI4Pain Grand Challenge 2025: Advancing Pain Assessment with Multimodal Physiological Signals
Fernandez-Rojas R, Joseph C, Hirachan N, Seymour B & Goecke R (2025), 147-152
BibTeX
@inproceedings{theaipaingrandc-2025/10,
title={The AI4Pain Grand Challenge 2025: Advancing Pain Assessment with Multimodal Physiological Signals},
author={Fernandez-Rojas R, Joseph C, Hirachan N, Seymour B & Goecke R},
booktitle={Companion Proceedings of the 27th International Conference on Multimodal Interaction},
pages={147-152},
year = "2025"
}
Characterization of CNS Network Changes in Two Rodent Models of Chronic Pain
Sprenger C, Kanbara T, Yamada T, Morikawa Y, Koda K et al. (2025), Biological and Pharmaceutical Bulletin, 48(9), 1358-1374
Short-term variability of chronic musculoskeletal pain
Zheng X, Rajwal S, Ashworth C, Ho SYS, Seymour B et al. (2025), Frontiers in Pain Research, 6
Brain signatures of nociplastic pain: Fibromyalgia Index and descending modulation at population level
Kelleher EM, Lange F, Wanigasekera V, Rathod-Mistry T, Nichols T et al. (2025), Brain, awaf307
BibTeX
@article{brainsignatures-2025/8,
title={Brain signatures of nociplastic pain: Fibromyalgia Index and descending modulation at population level},
author={Kelleher EM, Lange F, Wanigasekera V, Rathod-Mistry T, Nichols T et al.},
journal={Brain},
pages={awaf307},
publisher={Oxford University Press (OUP)},
year = "2025"
}
Neurofeedback modulation of insula activity via MEG-based brain-machine interface: a double-blind randomized controlled crossover trial
Wang Y, Fukuma R, Seymour B, Yang H, Kishima H et al. (2025), Communications Biology, 8(1)
BibTeX
@article{neurofeedbackmo-2025/5,
title={Neurofeedback modulation of insula activity via MEG-based brain-machine interface: a double-blind randomized controlled crossover trial},
author={Wang Y, Fukuma R, Seymour B, Yang H, Kishima H et al.},
journal={Communications Biology},
volume={8},
number={770},
publisher={Nature Research},
year = "2025"
}
How the magnitude and precision of pain predictions shape pain experiences
Derksen SMJC, Konttinen M, Myronenko A, Seymour B & Peerdeman KJ (2024), European Journal of Pain, 29(1)
Enhanced behavioural and neural sensitivity to punishments in chronic pain and fatigue
Mancini F, Mahajan P, Guttesen AÁ, Onysk J, Scholtes I et al. (2024), Brain, 148(6), 2151-2162
BibTeX
@article{enhancedbehavio-2024/12,
title={Enhanced behavioural and neural sensitivity to punishments in chronic pain and fatigue},
author={Mancini F, Mahajan P, Guttesen AÁ, Onysk J, Scholtes I et al.},
journal={Brain},
volume={148},
pages={2151-2162},
publisher={Oxford University Press},
year = "2024"
}
Automated Assessment of Pain (AAP) and Multimodal Sensing Grand Challenge for Next-Gen Pain Assessment (AI4Pain)
Hammal Z, Walter S, Berthouze N, Fernandez-Rojas R, Seymour B et al. (2024), 00, 1-3
BibTeX
@inproceedings{automatedassess-2024/1,
title={Automated Assessment of Pain (AAP) and Multimodal Sensing Grand Challenge for Next-Gen Pain Assessment (AI4Pain)},
author={Hammal Z, Walter S, Berthouze N, Fernandez-Rojas R, Seymour B et al.},
booktitle={2024 12th International Conference on Affective Computing and Intelligent Interaction Workshops and Demos (ACIIW)},
pages={1-3},
year = "2024"
}
The AI4Pain Grand Challenge 2024: Advancing Pain Assessment with Multimodal fNIRS and Facial Video Analysis
Fernandez–Rojas R, Joseph C, Hirachan N, Seymour B & Goecke R (2024), 00, 55-60
BibTeX
@inproceedings{theaipaingrandc-2024/1,
title={The AI4Pain Grand Challenge 2024: Advancing Pain Assessment with Multimodal fNIRS and Facial Video Analysis},
author={Fernandez–Rojas R, Joseph C, Hirachan N, Seymour B & Goecke R},
booktitle={2024 12th International Conference on Affective Computing and Intelligent Interaction Workshops and Demos (ACIIW)},
pages={55-60},
year = "2024"
}
Multimodal physiological sensing for the assessment of acute pain
Rojas RF, Hirachan N, Brown N, Waddington G, Murtagh L et al. (2023), Frontiers in Pain Research, 4, 1150264-1150264
BibTeX
@article{multimodalphysi-2023/6,
title={Multimodal physiological sensing for the assessment of acute pain},
author={Rojas RF, Hirachan N, Brown N, Waddington G, Murtagh L et al.},
journal={Frontiers in Pain Research},
volume={4},
number={1150264},
pages={1150264-1150264},
publisher={Frontiers Media},
year = "2023"
}
Post-injury pain and behaviour: a control theory perspective
Seymour B, Crook RJ & Chen ZS (2023), Nature Reviews Neuroscience, 24(6), 378-392
Post-injury pain and behaviour: a control theory perspective.
Seymour B, Crook RJ & Chen ZS (2023), Nature reviews. Neuroscience, 24(6), 378-392
Improving sleep and learning in rehabilitation after stroke, part 2 (INSPIRES2): study protocol for a home-based randomised control trial of digital cognitive behavioural therapy (dCBT) for insomnia
Weightman M, Robinson B, Fallows R, Henry AL, Kyle SD et al. (2023), BMJ Open, 13(4)
BibTeX
@article{improvingsleepa-2023/4,
title={Improving sleep and learning in rehabilitation after stroke, part 2 (INSPIRES2): study protocol for a home-based randomised control trial of digital cognitive behavioural therapy (dCBT) for insomnia},
author={Weightman M, Robinson B, Fallows R, Henry AL, Kyle SD et al.},
journal={BMJ Open},
volume={13},
number={e071764},
publisher={BMJ Publishing Group},
year = "2023"
}
Improving sleep and learning in rehabilitation after stroke, part 2 (INSPIRES2): study protocol for a home-based randomised control trial of digital cognitive behavioural therapy (dCBT) for insomnia.
Weightman M, Robinson B, Fallows R, Henry AL, Kyle SD et al. (2023), BMJ open, 13(4), e071764
BibTeX
@article{improvingsleepa-2023/4,
title={Improving sleep and learning in rehabilitation after stroke, part 2 (INSPIRES2): study protocol for a home-based randomised control trial of digital cognitive behavioural therapy (dCBT) for insomnia.},
author={Weightman M, Robinson B, Fallows R, Henry AL, Kyle SD et al.},
journal={BMJ open},
volume={13},
pages={e071764},
year = "2023"
}
Evidence for dopaminergic involvement in endogenous modulation of pain relief
Desch S, Schweinhardt P, Seymour B, Flor H & Becker S (2023), eLife, 12, e81436
BibTeX
@article{evidencefordopa-2023/2,
title={Evidence for dopaminergic involvement in endogenous modulation of pain relief},
author={Desch S, Schweinhardt P, Seymour B, Flor H & Becker S},
journal={eLife},
volume={12},
number={e81436},
pages={e81436},
publisher={eLife Sciences Publications},
year = "2023"
}
Confidence of probabilistic predictions modulates the cortical response to pain
Mulders D, Seymour B, Mouraux A & Mancini F (2023), Proceedings of the National Academy of Sciences of the United States of America, 120(4), e2212252120
BibTeX
@article{confidenceofpro-2023/1,
title={Confidence of probabilistic predictions modulates the cortical response to pain},
author={Mulders D, Seymour B, Mouraux A & Mancini F},
journal={Proceedings of the National Academy of Sciences of the United States of America},
volume={120},
pages={e2212252120},
publisher={Proceedings of the National Academy of Sciences},
year = "2023"
}
Multimodal physiological sensing for the assessment of acute pain.
Fernandez Rojas R, Hirachan N, Brown N, Waddington G, Murtagh L et al. (2023), Frontiers in pain research (Lausanne, Switzerland), 4, 1150264
BibTeX
@article{multimodalphysi-2023/1,
title={Multimodal physiological sensing for the assessment of acute pain.},
author={Fernandez Rojas R, Hirachan N, Brown N, Waddington G, Murtagh L et al.},
journal={Frontiers in pain research (Lausanne, Switzerland)},
volume={4},
pages={1150264},
year = "2023"
}
Neurofeedback Training without Explicit Phantom Hand Movements and Hand-Like Visual Feedback to Modulate Pain: A Randomized Crossover Feasibility Trial
Yanagisawa T, Fukuma R, Seymour B, Tanaka M, Yamashita O et al. (2022), Journal of Pain, 23(12), 2080-2091
BibTeX
@article{neurofeedbacktr-2022/12,
title={Neurofeedback Training without Explicit Phantom Hand Movements and Hand-Like Visual Feedback to Modulate Pain: A Randomized Crossover Feasibility Trial},
author={Yanagisawa T, Fukuma R, Seymour B, Tanaka M, Yamashita O et al.},
journal={Journal of Pain},
volume={23},
pages={2080-2091},
publisher={Elsevier},
year = "2022"
}
Computational and neural mechanisms of statistical pain learning
Mancini F, Zhang S & Seymour B (2022), Nature Communications, 13(1), 6613-6613
Endogenous modulation of pain relief: evidence for dopaminergic but not opioidergic involvement
Desch S, Schweinhardt P, Seymour B, Flor H & Becker S (2022)
A multi-site, multi-disorder resting-state magnetic resonance image database
Tanaka SC, Yamashita A, Yahata N, Yoshida W & Seymour B (2021), Scientific Data, 8(1)
Pain Control by Co-adaptive Learning in a Brain-Machine Interface
Zhang S, Yoshida W, Mano H, Yanagisawa T, Mancini F et al. (2020), Current Biology, 30(20), 3935-3944.e7
Reward Enhances Pain Discrimination in Humans
Becker S, Löffler M & Seymour B (2020), Psychological Science, 31(9), 1191-1199
Hierarchical models of pain: inference, information-seeking, and adaptive control
Seymour B & Mancini F (2020), NeuroImage, 222
Resting-state Amplitude of Low-frequency Fluctuation is a Potentially Useful Prognostic Functional Biomarker in Cervical Myelopathy.
Takenaka S, Kan S, Seymour B, Makino T, Sakai Y et al. (2020), Clinical Orthopaedics and Related Research®, 478(7), 1667-1680
BibTeX
@article{restingstateamp-2020/7,
title={Resting-state Amplitude of Low-frequency Fluctuation is a Potentially Useful Prognostic Functional Biomarker in Cervical Myelopathy.},
author={Takenaka S, Kan S, Seymour B, Makino T, Sakai Y et al.},
journal={Clinical Orthopaedics and Related Research®},
volume={478},
pages={1667-1680},
publisher={Wolters Kluwer},
year = "2020"
}
BCI training to move a virtual hand reduces phantom limb pain: A randomized crossover trial
Yanagisawa T, Fukuma R, Seymour B, Tanaka M, Hosomi K et al. (2020), Neurology, 95(4), 10.1212/wnl.0000000000009858
BibTeX
@article{bcitrainingtomo-2020/7,
title={BCI training to move a virtual hand reduces phantom limb pain: A randomized crossover trial},
author={Yanagisawa T, Fukuma R, Seymour B, Tanaka M, Hosomi K et al.},
journal={Neurology},
volume={95},
pages={10.1212/wnl.0000000000009858},
publisher={Wolters Kluwer},
year = "2020"
}
Editorial overview: Pain and aversive motivation
Johansen JP & Seymour B (2019), Current Opinion in Behavioral Sciences, 26, iii-v
Decision-making in brains and robots — the case for an interdisciplinary approach
Lee SW & Seymour B (2019), Current Opinion in Behavioral Sciences, 26, 137-145
Pain: A Precision Signal for Reinforcement Learning and Control
Seymour B (2019), Neuron, 101(6), 1029-1041
Toward high-performance, memory-efficient, and fast reinforcement learning—Lessons from decision neuroscience
Lee JH, Seymour B, Leibo JZ, An SJ & Lee SW (2019), Science Robotics, 4(26)
BibTeX
@article{towardhighperfo-2019/1,
title={Toward high-performance, memory-efficient, and fast reinforcement learning—Lessons from decision neuroscience},
author={Lee JH, Seymour B, Leibo JZ, An SJ & Lee SW},
journal={Science Robotics},
volume={4},
publisher={American Association for the Advancement of Science (AAAS)},
year = "2019"
}
MEG–BMI to Control Phantom Limb Pain
YANAGISAWA T, FUKUMA R, SEYMOUR B, HOSOMI K, KISHIMA H et al. (2018), Neurologia Medico-Chirurgica, 58(8), st.2018-st.0099
Thermosensory Perceptual Learning Is Associated with Structural Brain Changes in Parietal–Opercular (SII) Cortex
Mano H, Yoshida W, Shibata K, Zhang S, Koltzenburg M et al. (2017), Journal of Neuroscience, 37(39), 9380-9388
BibTeX
@article{thermosensorype-2017/9,
title={Thermosensory Perceptual Learning Is Associated with Structural Brain Changes in Parietal–Opercular (SII) Cortex},
author={Mano H, Yoshida W, Shibata K, Zhang S, Koltzenburg M et al.},
journal={Journal of Neuroscience},
volume={37},
pages={9380-9388},
publisher={Society for Neuroscience},
year = "2017"
}
Decoding Acute Pain with Combined EEG and Physiological Data
Lancaster J, Mano H, Callan D, Kawato M & Seymour B (2017), 521-524
Disrupted habenula function in major depression
Lawson RP, Nord CL, Seymour B, Thomas DL, Dayan P et al. (2017), Molecular Psychiatry, 22(2), 202-208
Pain and Self-Preservation in Autonomous Robots: From Neurobiological Models to Psychiatric Disease
Piccolo L, Liberal FD, Bonarini A, Scymour B & Ishiguro H (2017), 263-270
BibTeX
@inproceedings{painandselfpres-2017/1,
title={Pain and Self-Preservation in Autonomous Robots: From Neurobiological Models to Psychiatric Disease},
author={Piccolo L, Liberal FD, Bonarini A, Scymour B & Ishiguro H},
booktitle={2017 Joint IEEE International Conference on Development and Learning and Epigenetic Robotics (ICDL-EpiRob)},
pages={263-270},
year = "2017"
}
Parallel Reward and Punishment Control in Humans and Robots: Safe Reinforcement Learning Using the MaxPain Algorithm
Elfwing S & Seymour B (2017), 140-147
BibTeX
@inproceedings{parallelrewarda-2017/1,
title={Parallel Reward and Punishment Control in Humans and Robots: Safe Reinforcement Learning Using the MaxPain Algorithm},
author={Elfwing S & Seymour B},
booktitle={2017 Joint IEEE International Conference on Development and Learning and Epigenetic Robotics (ICDL-EpiRob)},
pages={140-147},
year = "2017"
}
Anterior cingulate cortex connectivity is associated with suppression of behavior in a rat model of chronic pain
Morris L, Sprenger C, Koda K, de la Mora D, Yamada T et al. (2017)
Dissociable Learning Processes Underlie Human Pain Conditioning
Zhang S, Mano H, Ganesh G, Robbins T & Seymour B (2016), Current Biology, 26(1), 52-58
Fear reduction without fear through reinforcement of neural activity that bypasses conscious exposure
Koizumi A, Amano K, Cortese A, Shibata K, Yoshida W et al. (2016), Nature Human Behaviour, 1(1), 0006
BibTeX
@article{fearreductionwi-2016/,
title={Fear reduction without fear through reinforcement of neural activity that bypasses conscious exposure},
author={Koizumi A, Amano K, Cortese A, Shibata K, Yoshida W et al.},
journal={Nature Human Behaviour},
volume={1},
pages={0006},
publisher={Springer Nature},
year = "2016"
}
When is a loss a loss? Excitatory and inhibitory processes in loss-related decision-making
Seymour B, Maruyama M & De Martino B (2015), Current Opinion in Behavioral Sciences, 5, 122-127
BibTeX
@article{whenisalossalos-2015/10,
title={When is a loss a loss? Excitatory and inhibitory processes in loss-related decision-making},
author={Seymour B, Maruyama M & De Martino B},
journal={Current Opinion in Behavioral Sciences},
volume={5},
pages={122-127},
publisher={Elsevier},
year = "2015"
}
Distinct Contributions of Ventromedial and Dorsolateral Subregions of the Human Substantia Nigra to Appetitive and Aversive Learning
Pauli WM, Larsen T, Collette S, Tyszka JM, Seymour B et al. (2015), Journal of Neuroscience, 35(42), 14220-14233
BibTeX
@article{distinctcontrib-2015/10,
title={Distinct Contributions of Ventromedial and Dorsolateral Subregions of the Human Substantia Nigra to Appetitive and Aversive Learning},
author={Pauli WM, Larsen T, Collette S, Tyszka JM, Seymour B et al.},
journal={Journal of Neuroscience},
volume={35},
pages={14220-14233},
publisher={Society for Neuroscience},
year = "2015"
}
Modulating the pain network—neurostimulation for central poststroke pain
Hosomi K, Seymour B & Saitoh Y (2015), Nature Reviews Neurology, 11(5), 290-299