Showing 50 publications by Tim Denison
Flexible and stable cycle-by-cycle phase-locked deep brain stimulation system targeting brain oscillations in the management of movement disorders
Guo X, Pogosyan A, Debarros J, He S, Wehmeyer L et al. (2025), Brain Stimulation, 18(5), 1705-1717
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                            @article{flexibleandstab-2025/9,
  title={Flexible and stable cycle-by-cycle phase-locked deep brain stimulation system targeting brain oscillations in the management of movement disorders},
  author={Guo X, Pogosyan A, Debarros J, He S, Wehmeyer L et al.},
  journal={Brain Stimulation},
  volume={18},
  pages={1705-1717},
  publisher={Elsevier},
  year = "2025"
}
Seizure forecasting by tracking cortical response to electrical stimulation
Laiou P, Kraljevic Z, Valentin A, Jewell S, Viana PF et al. (2025), Epilepsia: Official journal of the International League Against Epilepsy
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                            @article{seizureforecast-2025/7,
  title={Seizure forecasting by tracking cortical response to electrical stimulation},
  author={Laiou P, Kraljevic Z, Valentin A, Jewell S, Viana PF et al.},
  journal={Epilepsia: Official journal of the International League Against Epilepsy},
  publisher={Wiley},
  year = "2025"
}
Assessing Phase-Locked Repetitive Transcranial Magnetic Stimulation for Treatment of Parkinson’s and Essential Tremor
Sharma P, Vasaturo-Kolodner T, Mancini V, Shackle N, Wendt K et al. (2025), Brain Stimulation, 18(4), 1292-1293
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                            @article{assessingphasel-2025/7,
  title={Assessing Phase-Locked Repetitive Transcranial Magnetic Stimulation for Treatment of Parkinson’s and Essential Tremor},
  author={Sharma P, Vasaturo-Kolodner T, Mancini V, Shackle N, Wendt K et al.},
  journal={Brain Stimulation},
  volume={18},
  pages={1292-1293},
  publisher={Elsevier},
  year = "2025"
}
Modulating limbic circuits in temporal lobe epilepsy: impacts on seizures, memory, mood and sleep
Kremen V, Sladky V, Mivalt F, Gregg NM, Brinkmann BH et al. (2025), Brain Communications, 7(2)
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                            @article{modulatinglimbi-2025/4,
  title={Modulating limbic circuits in temporal lobe epilepsy: impacts on seizures, memory, mood and sleep},
  author={Kremen V, Sladky V, Mivalt F, Gregg NM, Brinkmann BH et al.},
  journal={Brain Communications},
  volume={7},
  number={fcaf106},
  publisher={Oxford University Press},
  year = "2025"
}
Augmenting rehabilitation robotics with spinal cord neuromodulation: A proof of concept.
Hankov N, Caban M, Demesmaeker R, Roulet M, Komi S et al. (2025), Science robotics, 10(100), eadn5564
Reducing inequalities through greater diversity in clinical trials – as important for medical devices as for drugs and therapeutics
Roope LSJ, Walsh J, Welland M, Samuel G, Johansen-Berg H et al. (2025), Contemporary Clinical Trials Communications, 101467
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                            @article{reducinginequal-2025/3,
  title={Reducing inequalities through greater diversity in clinical trials – as important for medical devices as for drugs and therapeutics},
  author={Roope LSJ, Walsh J, Welland M, Samuel G, Johansen-Berg H et al.},
  journal={Contemporary Clinical Trials Communications},
  pages={101467},
  publisher={Elsevier},
  year = "2025"
}
Multi-level encoding of reward, effort and choice across the frontal cortex and basal ganglia during cost-benefit decision making
Harmson O, Grennan I, Perry B, Toth R, McNamara C et al. (2025), Cell Reports, 44(2)
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                            @article{multilevelencod-2025/1,
  title={Multi-level encoding of reward, effort and choice across the frontal cortex and basal ganglia during cost-benefit decision making},
  author={Harmson O, Grennan I, Perry B, Toth R, McNamara C et al.},
  journal={Cell Reports},
  volume={44},
  number={115209},
  publisher={Cell Press},
  year = "2025"
}
Modeling the determinants of attrition in a two-stage epilepsy prevalence survey in Nairobi using machine learning
Mwanga DM, Kipchirchir IC, Muhua GO, Newton CR, Kadengye DT et al. (2025), Global Epidemiology, 9, 100183
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                            @article{modelingthedete-2025/1,
  title={Modeling the determinants of attrition in a two-stage epilepsy prevalence survey in Nairobi using machine learning},
  author={Mwanga DM, Kipchirchir IC, Muhua GO, Newton CR, Kadengye DT et al.},
  journal={Global Epidemiology},
  volume={9},
  number={100183},
  pages={100183},
  publisher={Elsevier},
  year = "2025"
}
On brain stimulation in epilepsy.
Trevelyan AJ, Marks VS, Graham RT, Denison T, Jackson A et al. (2025), Brain : a journal of neurology, awae385
An application-based taxonomy for brain-computer interfaces.
Robinson JT, Norman SL, Angle MR, Constandinou TG, Denison T et al. (2024), Nature biomedical engineering
Challenges and opportunities of acquiring cortical recordings for chronic adaptive deep brain stimulation.
Herron J, Kullmann A, Denison T, Goodman WK, Gunduz A et al. (2024), Nature biomedical engineering
A survey of few-shot learning for biomedical time series
Li C, Denison T & Zhu T (2024), IEEE Reviews in Biomedical Engineering, 18, 192-210
A digital dashboard for reporting mental, neurological and substance use disorders in Nairobi, Kenya: Implementing an open source data technology for improving data capture
Mwanga DM, Waruingi S, Manolova G, Wekesah FM, Kadengye DT et al. (2024), PLOS Digital Health, 3(11)
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                            @article{adigitaldashboa-2024/11,
  title={A digital dashboard for reporting mental, neurological and substance use disorders in Nairobi, Kenya: Implementing an open source data technology for improving data capture},
  author={Mwanga DM, Waruingi S, Manolova G, Wekesah FM, Kadengye DT et al.},
  journal={PLOS Digital Health},
  volume={3},
  number={e0000646},
  publisher={Public Library of Science},
  year = "2024"
}
Development and evaluation of a real-time phase-triggered stimulation algorithm for the CorTec Brain Interchange
Cho H, Benjaber M, Alexis Gkogkidis C, Buchheit M, Ruiz-Rodriguez JF et al. (2024), IEEE Transactions on Neural Systems and Rehabilitation Engineering, 32, 3625-3635
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                            @article{developmentande-2024/9,
  title={Development and evaluation of a real-time phase-triggered stimulation algorithm for the CorTec Brain Interchange},
  author={Cho H, Benjaber M, Alexis Gkogkidis C, Buchheit M, Ruiz-Rodriguez JF et al.},
  journal={IEEE Transactions on Neural Systems and Rehabilitation Engineering},
  volume={32},
  pages={3625-3635},
  publisher={IEEE},
  year = "2024"
}
Offline hippocampal reactivation during dentate spikes supports flexible memory
McHugh S, Lopes Dos Santos V, Castelli M, Gava G, Thompson S et al. (2024), Neuron, 112(22), p3768-3781.e8
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                            @article{offlinehippocam-2024/9,
  title={Offline hippocampal reactivation during dentate spikes supports flexible memory},
  author={McHugh S, Lopes Dos Santos V, Castelli M, Gava G, Thompson S et al.},
  journal={Neuron},
  volume={112},
  pages={p3768-3781.e8},
  publisher={Cell Press},
  year = "2024"
}
Pudendal nerve stimulation for treatment of lower urinary tract symptoms: A systematic review of safety, technical feasibility and clinical efficacy
Herroelen S, Knowles C, Kerrigan-Smith J, Noone T, Denison T et al. (2024), Continence, 11, 101685
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                            @article{pudendalnervest-2024/9,
  title={Pudendal nerve stimulation for treatment of lower urinary tract symptoms: A systematic review of safety, technical feasibility and clinical efficacy},
  author={Herroelen S, Knowles C, Kerrigan-Smith J, Noone T, Denison T et al.},
  journal={Continence},
  volume={11},
  pages={101685},
  publisher={Elsevier},
  year = "2024"
}
Attitudes and perceptions towards epilepsy in an onchocerciasis-endemic region of Tanzania: a mixed approach to determine the magnitude and driving factors
Mushi VP, Kidima W, Massawe IS, Magili PF, Bhwana D et al. (2024), BMC Public Health, 24(1)
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                            @article{attitudesandper-2024/9,
  title={Attitudes and perceptions towards epilepsy in an onchocerciasis-endemic region of Tanzania: a mixed approach to determine the magnitude and driving factors},
  author={Mushi VP, Kidima W, Massawe IS, Magili PF, Bhwana D et al.},
  journal={BMC Public Health},
  volume={24},
  number={2608},
  publisher={BioMed Central},
  year = "2024"
}
Longevity of a brain-computer interface for amyotrophic lateral sclerosis
Vansteensel MJ, Leinders S, Branco MP, Crone NE, Denison T et al. (2024), New England Journal of Medicine, 391(7), 619-626
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                            @article{longevityofabra-2024/8,
  title={Longevity of a brain-computer interface for amyotrophic lateral sclerosis},
  author={Vansteensel MJ, Leinders S, Branco MP, Crone NE, Denison T et al.},
  journal={New England Journal of Medicine},
  volume={391},
  pages={619-626},
  publisher={Massachusetts Medical Society},
  year = "2024"
}
Translation of neurotechnologies
Schalk G, Brunner P, Allison BZ, Soekadar SR, Guan C et al. (2024), Nature Reviews Bioengineering, 2(8), 637-652
The convergence of neuromodulation and brain–computer interfaces
Herron J, Kremen V, Simeral JD, Dawes H, Worrell GA et al. (2024), Nature Reviews Bioengineering, 2(8), 628-630
Challenges and opportunities for physiologically controlled therapy in neural systems
Marks VS, Piper RJ, Van Rheede JJ, Benjaber M, Green AL et al. (2024), IEEE Pulse, 15(2), 15-20
"EpilepSee" Glasses: A Wearable Seizure Prevention Device for Photosensitive Epilepsy.
Crooks G, Perks J, Gawne F, Ali H, Steel H et al. (2024), Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2024, 1-4
Evoked resonant neural activity long-term dynamics can be reproduced by a computational model with vesicle depletion.
Sermon JJ, Wiest C, Tan H, Denison T & Duchet B (2024), Neurobiology of disease, 199, 106565
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                            @article{evokedresonantn-2024/6,
  title={Evoked resonant neural activity long-term dynamics can be reproduced by a computational model with vesicle depletion.},
  author={Sermon JJ, Wiest C, Tan H, Denison T & Duchet B},
  journal={Neurobiology of disease},
  volume={199},
  pages={106565},
  publisher={Elsevier},
  year = "2024"
}
A platform for brain network sensing and stimulation with quantitative behavioral tracking: Application to limbic circuit epilepsy.
Kremen V, Sladky V, Mivalt F, Gregg NM, Balzekas I et al. (2024)
Acute to long-term characteristics of impedance recordings during neurostimulation in humans
Cui J, Mivalt F, Sladky V, Kim J, Richner TJ et al. (2024), Journal of Neural Engineering, 21(2)
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                            @article{acutetolongterm-2024/4,
  title={Acute to long-term characteristics of impedance recordings during neurostimulation in humans},
  author={Cui J, Mivalt F, Sladky V, Kim J, Richner TJ et al.},
  journal={Journal of Neural Engineering},
  volume={21},
  number={026022},
  publisher={IOP Publishing},
  year = "2024"
}
Pre-existing oscillatory activity as a condition for sub-harmonic entrainment of finely tuned gamma in Parkinson's disease
Sermon J, Starr PA, Denison T & Duchet B (2024), Brain Stimulation, 17(2), 488-490
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                            @article{preexistingosci-2024/4,
  title={Pre-existing oscillatory activity as a condition for sub-harmonic entrainment of finely tuned gamma in Parkinson's disease},
  author={Sermon J, Starr PA, Denison T & Duchet B},
  journal={Brain Stimulation},
  volume={17},
  pages={488-490},
  publisher={Elsevier},
  year = "2024"
}
Definition of Implanted Neurological Device Abandonment: A Systematic Review and Consensus Statement.
Okun MS, Marjenin T, Ekanayake J, Gilbert F, Doherty SP et al. (2024), JAMA network open, 7(4), e248654-e248654
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                            @article{definitionofimp-2024/4,
  title={Definition of Implanted Neurological Device Abandonment: A Systematic Review and Consensus Statement.},
  author={Okun MS, Marjenin T, Ekanayake J, Gilbert F, Doherty SP et al.},
  journal={JAMA network open},
  volume={7},
  pages={e248654-e248654},
  year = "2024"
}
Multi-night cortico-basal recordings reveal mechanisms of NREM slow-wave suppression and spontaneous awakenings in Parkinson's disease
Anjum MF, Smyth C, Zuzuárregui R, Dijk DJ, Starr PA et al. (2024), Nature Communications, 15(1)
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                            @article{multinightcorti-2024/2,
  title={Multi-night cortico-basal recordings reveal mechanisms of NREM slow-wave suppression and spontaneous awakenings in Parkinson's disease},
  author={Anjum MF, Smyth C, Zuzuárregui R, Dijk DJ, Starr PA et al.},
  journal={Nature Communications},
  volume={15},
  number={1793},
  publisher={Springer Nature},
  year = "2024"
}
Cortical signatures of sleep are altered following effective deep brain stimulation for depression
van Rheede JJ, Alagapan S, Denison TJ, Riva-Posse P, Rozell CJ et al. (2024), Translational Psychiatry, 14(1)
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                            @article{corticalsignatu-2024/2,
  title={Cortical signatures of sleep are altered following effective deep brain stimulation for depression},
  author={van Rheede JJ, Alagapan S, Denison TJ, Riva-Posse P, Rozell CJ et al.},
  journal={Translational Psychiatry},
  volume={14},
  number={103},
  publisher={Springer Nature},
  year = "2024"
}
1:2 entrainment is not a device-induced artefact, except when it is
Sermon J, Benjaber M, Duchet B, Anso J, Olaru M et al. (2024), Brain Stimulation, 17(2), 149-151
Acute to long-term characteristics of impedance recordings during neurostimulation in humans
Cui J, Mivalt F, Sladky V, Kim J, Richner TJ et al. (2024)
Bioelectronic Zeitgebers: targeted neuromodulation to re-establish circadian rhythms.
Deli A, Zamora M, Fleming JE, Divanbeighi Zand A, Benjaber M et al. (2024), Conference proceedings. IEEE International Conference on Systems, Man, and Cybernetics, 2023, 2301-2308
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                            @article{bioelectronicze-2024/1,
  title={Bioelectronic Zeitgebers: targeted neuromodulation to re-establish circadian rhythms.},
  author={Deli A, Zamora M, Fleming JE, Divanbeighi Zand A, Benjaber M et al.},
  journal={Conference proceedings. IEEE International Conference on Systems, Man, and Cybernetics},
  volume={2023},
  pages={2301-2308},
  publisher={Institute of Electrical and Electronics Engineers (IEEE)},
  year = "2024"
}
MorpheusNet: Resource efficient sleep stage classifier for embedded on-line systems
Kavoosi A, Mitchell MP, Kariyawasam R, Fleming JE, Lewis P et al. (2024)
Prediction of pathological subthalamic nucleus beta burst occurrence in Parkinson’s disease
Abdi-Sargezeh B, Shirani S, Sharma A, Green A, Akram H et al. (2024)
An embedded intracranial seizure monitor for objective outcome measurements and rhythm identification
Fleming J, Benjaber M, Toth R, Zamora M, Landin K et al. (2023), Proceedings of the 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC 2023), 1-6
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                            @inproceedings{anembeddedintra-2023/12,
  title={An embedded intracranial seizure monitor for objective outcome measurements and rhythm identification},
  author={Fleming J, Benjaber M, Toth R, Zamora M, Landin K et al.},
  booktitle={45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC 2023)},
  pages={1-6},
  year = "2023"
}
From dawn till dusk: time-adaptive bayesian optimization for neurostimulation
Fleming JE, Pont Sanchis I, Lemmens O, Denison-Smith A, West TO et al. (2023), PLoS Computational Biology, 19(12)
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                            @article{fromdawntilldus-2023/12,
  title={From dawn till dusk: time-adaptive bayesian optimization for neurostimulation},
  author={Fleming JE, Pont Sanchis I, Lemmens O, Denison-Smith A, West TO et al.},
  journal={PLoS Computational Biology},
  volume={19},
  number={e1011674},
  publisher={Public Library of Science},
  year = "2023"
}
MorpheusNet: Resource efficient sleep stage classifier for embedded on-line systems.
Kavoosi A, Mitchell MP, Kariyawasam R, Fleming JE, Lewis P et al. (2023), Conference proceedings. IEEE International Conference on Systems, Man, and Cybernetics, 2023, 2315-2320
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                            @article{morpheusnetreso-2023/10,
  title={MorpheusNet: Resource efficient sleep stage classifier for embedded on-line systems.},
  author={Kavoosi A, Mitchell MP, Kariyawasam R, Fleming JE, Lewis P et al.},
  journal={Conference proceedings. IEEE International Conference on Systems, Man, and Cybernetics},
  volume={2023},
  pages={2315-2320},
  year = "2023"
}
Adaptive Deep Brain Stimulation for sleep stage targeting in Parkinson's disease.
Smyth C, Anjum MF, Ravi S, Denison T, Starr P et al. (2023), Brain stimulation, 16(5), 1292-1296
Influence of time of day on resting motor threshold in clinical TMS practice
Wendt K, Sorkhabi MM, O'Shea J, Denison T & van Rheede J (2023), Clinical Neurophysiology, 155, 65-67
Sub-harmonic entrainment of cortical gamma oscillations to deep brain stimulation in Parkinson's disease: model based predictions and validation in three human subjects
Sermon J, Olaru M, Ansó J, Cernera S, Little S et al. (2023), Brain Stimulation, 16(5), 1412-1424
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                            @article{subharmonicentr-2023/9,
  title={Sub-harmonic entrainment of cortical gamma oscillations to deep brain stimulation in Parkinson's disease: model based predictions and validation in three human subjects},
  author={Sermon J, Olaru M, Ansó J, Cernera S, Little S et al.},
  journal={Brain Stimulation},
  volume={16},
  pages={1412-1424},
  publisher={Elsevier},
  year = "2023"
}
Automated sleep classification with chronic neural implants in freely behaving canines
Mivalt F, Sladky V, Worrell S, Gregg NM, Balzekas I et al. (2023), Journal of Neural Engineering, 20(4)
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                            @article{automatedsleepc-2023/8,
  title={Automated sleep classification with chronic neural implants in freely behaving canines},
  author={Mivalt F, Sladky V, Worrell S, Gregg NM, Balzekas I et al.},
  journal={Journal of Neural Engineering},
  volume={20},
  number={046025},
  publisher={IOP Publishing},
  year = "2023"
}
The effect of pulse shape in theta-burst stimulation: monophasic vs biphasic TMS
Wendt K, Sorkhabi MM, Stagg CJ, Fleming MK, Denison T et al. (2023), Brain Stimulation, 16(4), 1178-1185
Adaptive deep brain stimulation for sleep stage targeting in Parkinson's disease
Smyth C, Anjum MF, Ravi S, Denison T, Starr P et al. (2023), Brain Stimulation, 16(5), 1292-1296
Impedance rhythms in human limbic system
Mivalt F, Kremen V, Sladky V, Cui J, Gregg NM et al. (2023), Journal of Neuroscience, 43(39), 6653-6666
Beta-triggered adaptive deep brain stimulation during reaching movement in Parkinson's disease
He S, Baig F, Merla A, Torrecillos F, Perera A et al. (2023), Brain, 146(12), 5015-5030
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                            @article{betatriggeredad-2023/7,
  title={Beta-triggered adaptive deep brain stimulation during reaching movement in Parkinson's disease},
  author={He S, Baig F, Merla A, Torrecillos F, Perera A et al.},
  journal={Brain},
  volume={146},
  pages={5015-5030},
  publisher={Oxford University Press},
  year = "2023"
}
ID: 221007 Bioelectronic Zeitgebers: Towards Neuromodulation Devices Synchronized to Biological Rhythms
Fleming J, Noone T, Deli A, Zamora M, Zand AD et al. (2023), Neuromodulation Technology at the Neural Interface, 26(4), s123
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                            @article{idbioelectronic-2023/6,
  title={ID: 221007 Bioelectronic Zeitgebers: Towards Neuromodulation Devices Synchronized to Biological Rhythms},
  author={Fleming J, Noone T, Deli A, Zamora M, Zand AD et al.},
  journal={Neuromodulation Technology at the Neural Interface},
  volume={26},
  pages={s123},
  publisher={Elsevier},
  year = "2023"
}
xTMS: A pulse generator for exploring transcranial magnetic stimulation therapies
Ali K, Wendt K, Memarian Sorkhabi M, Benjaber M, Denison T et al. (2023), 2023 IEEE Applied Power Electronics Conference and Exposition (APEC), 1875-1880
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                            @inproceedings{xtmsapulsegener-2023/5,
  title={xTMS: A pulse generator for exploring transcranial magnetic stimulation therapies},
  author={Ali K, Wendt K, Memarian Sorkhabi M, Benjaber M, Denison T et al.},
  booktitle={IEEE Applied Power Electronics Conference & Exposition (APEC 2023)},
  pages={1875-1880},
  year = "2023"
}
Walking naturally after spinal cord injury using a brain–spine interface
Lorach H, Galvez A, Spagnolo V & Denison T (2023), Nature, 618(7963), 126-133
Regulation of arousal and performance of a healthy non-human primate using closed-loop central thalamic deep brain stimulation
Baker JL, Toth R, Deli A, Zamora M, Fleming JE et al. (2023), 2023 11th International IEEE/EMBS Conference on Neural Engineering (NER)
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                            @inproceedings{regulationofaro-2023/5,
  title={Regulation of arousal and performance of a healthy non-human primate using closed-loop central thalamic deep brain stimulation},
  author={Baker JL, Toth R, Deli A, Zamora M, Fleming JE et al.},
  booktitle={11th International IEEE EMBS Conference on Neural Engineering (NER 2023)},
  year = "2023"
}
Development and validation of a diagnostic aid for convulsive epilepsy in sub-Saharan Africa: a retrospective case-control study
Jones GD, Kariuki SM, Ngugi AK, Mwesige AK, Masanja H et al. (2023), The Lancet Digital Health, 5(4), e185-e193
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                            @article{developmentandv-2023/4,
  title={Development and validation of a diagnostic aid for convulsive epilepsy in sub-Saharan Africa: a retrospective case-control study},
  author={Jones GD, Kariuki SM, Ngugi AK, Mwesige AK, Masanja H et al.},
  journal={The Lancet Digital Health},
  volume={5},
  pages={e185-e193},
  publisher={Elsevier},
  year = "2023"
}