Biography
Professor Cathy Ye is Professor of Tissue Engineering in the Institute of Biomedical Engineering, Department of Engineering Science at University of Oxford and Director of the Oxford Centre for Tissue Engineering and Bioprocessing. Her research focuses on tissue engineering, stem cell technologies, biomaterials, and bioprocessing, with particular interests in developing experimental models, scalable cell culture systems, and regenerative approaches for biomedical applications.
She studied Chemical Engineering at Dalian University of Technology and completed a DPhil at the University of Oxford, where her doctoral research examined hollow fibre membrane bioreactors for growing three-dimensional bone tissue. Before taking up her current role, she held research and teaching positions at Oxford and Imperial College London.
Most Recent Publications
Fibrin scaffolds for angiogenesis in soft tissue models: a systematic review
Fibrin scaffolds for angiogenesis in soft tissue models: a systematic review
Proteome constrained metabolic modeling of Sus scrofa muscle stem cells for cultured meat production
Proteome constrained metabolic modeling of Sus scrofa muscle stem cells for cultured meat production
Predictive modeling of CHO cell culture using enzyme-constrained genome-scale metabolic models coupled with empirical regression
Predictive modeling of CHO cell culture using enzyme-constrained genome-scale metabolic models coupled with empirical regression
Small extracellular vesicles from human bone marrow mesenchymal stromal cells enhance migration and regulate reparative gene expression in dermal fibroblasts
Small extracellular vesicles from human bone marrow mesenchymal stromal cells enhance migration and regulate reparative gene expression in dermal fibroblasts
Engineering a long-lasting microvasculature in vitro model for traumatic injury research.
Engineering a long-lasting microvasculature in vitro model for traumatic injury research.
Research Interests
Within the broad research area of tissue engineering and stem cell technologies, Cathy’s specific research interests lie in three interconnected areas: in vitro cancer model, biomaterials and bioreactor for tissue engineering and stem cell expansion.
Research Groups
Current Projects
- Advanced human in vitro models of pain (funded by MRC for 4 years)
- UK Brain BioLink (UK Brain Biology Resource Link) (funded by MRC for 2.5 years)
- SimCells for Cultured Meat
- Engineering human neural networks (BBSRC for 5 years)
- Development of a smart bioreactor for mammalian adherent cell expansion for application to cell therapy - Grant (EPSRC First Grant (EP/H021442/1) from 1st Jan 2010 for two years)
- Development of bone-cartilage interface (EPSRC Studentship)
- Development of in vitro three-dimensional tumour models – a feasibility study (John Fell Fund, University of Oxford from 1st Oct 2008 for 18 months)
Most Recent Publications
Fibrin scaffolds for angiogenesis in soft tissue models: a systematic review
Fibrin scaffolds for angiogenesis in soft tissue models: a systematic review
Proteome constrained metabolic modeling of Sus scrofa muscle stem cells for cultured meat production
Proteome constrained metabolic modeling of Sus scrofa muscle stem cells for cultured meat production
Predictive modeling of CHO cell culture using enzyme-constrained genome-scale metabolic models coupled with empirical regression
Predictive modeling of CHO cell culture using enzyme-constrained genome-scale metabolic models coupled with empirical regression
Small extracellular vesicles from human bone marrow mesenchymal stromal cells enhance migration and regulate reparative gene expression in dermal fibroblasts
Small extracellular vesicles from human bone marrow mesenchymal stromal cells enhance migration and regulate reparative gene expression in dermal fibroblasts
Engineering a long-lasting microvasculature in vitro model for traumatic injury research.
Engineering a long-lasting microvasculature in vitro model for traumatic injury research.
Teaching
Lectures
- C10 Biosystem Modelling
- C23/BME2 Tissue Engineering
- B17/BME1 Biomechanics
Lab organisation
- Tissue Engineering Lab for MSc in Biomedical Engineering
- Biochemical Engineering Coursework Module
- Cell characterisation for Centre for Doctoral Training in Healthcare Innovation
Most Recent Publications
Fibrin scaffolds for angiogenesis in soft tissue models: a systematic review
Fibrin scaffolds for angiogenesis in soft tissue models: a systematic review
Proteome constrained metabolic modeling of Sus scrofa muscle stem cells for cultured meat production
Proteome constrained metabolic modeling of Sus scrofa muscle stem cells for cultured meat production
Predictive modeling of CHO cell culture using enzyme-constrained genome-scale metabolic models coupled with empirical regression
Predictive modeling of CHO cell culture using enzyme-constrained genome-scale metabolic models coupled with empirical regression
Small extracellular vesicles from human bone marrow mesenchymal stromal cells enhance migration and regulate reparative gene expression in dermal fibroblasts
Small extracellular vesicles from human bone marrow mesenchymal stromal cells enhance migration and regulate reparative gene expression in dermal fibroblasts
Engineering a long-lasting microvasculature in vitro model for traumatic injury research.
Engineering a long-lasting microvasculature in vitro model for traumatic injury research.
DPhil Opportunities
There are PhD projects available for interested candidates within the group research activities. Informal inquiries can be directed to Dr Cathy Ye. However, PhD applications have to be done through the university website.
Most Recent Publications
Fibrin scaffolds for angiogenesis in soft tissue models: a systematic review
Fibrin scaffolds for angiogenesis in soft tissue models: a systematic review
Proteome constrained metabolic modeling of Sus scrofa muscle stem cells for cultured meat production
Proteome constrained metabolic modeling of Sus scrofa muscle stem cells for cultured meat production
Predictive modeling of CHO cell culture using enzyme-constrained genome-scale metabolic models coupled with empirical regression
Predictive modeling of CHO cell culture using enzyme-constrained genome-scale metabolic models coupled with empirical regression
Small extracellular vesicles from human bone marrow mesenchymal stromal cells enhance migration and regulate reparative gene expression in dermal fibroblasts
Small extracellular vesicles from human bone marrow mesenchymal stromal cells enhance migration and regulate reparative gene expression in dermal fibroblasts
Engineering a long-lasting microvasculature in vitro model for traumatic injury research.
Engineering a long-lasting microvasculature in vitro model for traumatic injury research.
