Career
2000-Present: Donald Pollock Professor of Chemical Engineering, Oxford University
2000-Present: Professorial Fellow of Hertford College, Oxford
2001-2020 – Founding Director, Oxford Centre for Tissue Engineering and Bioprocessing
2005-2010 – Changjiang Visiting Professor, Dalian University of Technology, China
2004 – Braun Intertec Visiting Professor, University of Minnesota, USA
Oct 1999 – 2000: Reader in Engineering Science, Oxford University
Jan 1999 - Sep 1999 – Visiting Professor, Georgia Institute of Technology, USA
Oct 1994 – Sep 2000: Official Fellow and Engineering Tutor, Keble College, Oxford
Oct 1994 – Sep 1999: University Lecturer in Engineering Science, Oxford University
Apr 1991 – Sep 1994: Lecturer, Department of Chemical Engineering, University of Edinburgh, UK
May 1990 – Mar 1991: Research Fellow, Department of Pharmacy, University of Strathclyde, UK
Oct 1988 – Apr 1990: Research Associate, Bioengineering Unit, University of Strathclyde, UK
Education and Qualifications
Oct 1978 – Jul 1982 : BSc in Chemical Engineering,1982, Inner Mongolia Polytechnic University (China)
Sep 1982 – Dec 1985: MSc in Chemical Engineering, 1984, Dalian University of Technology (China)
Jan 1986 – Dec 1988: PhD in Chemical Engineering,1987, Dalian University of Technology (China)
MA, 1994, Keble College, Oxford
DSc, 2009, University of Oxford
CSci, 2004, The Science Council, UK
CEng, 1997, The Engineering Council, UK
Fellow, Institution of the Chemical Engineers (FIChemE), 2003
Fellow, American Institute for Medical and Biological Engineering, 2014
Other Roles
Editor-in-Chief: Bio-Design and Manufacturing
Trustee: Oxford China Scholarship Fund (COSF)
Research Interests
Regenerative Medical Engineering and Technologies
Bioreactor technology for tissue culture and stem cell expansion; Cryopreservation of stem cells and engineered tissue; Stem cell therapy for neural degeneration and repair.
Biomanufacture, Bioprocessing, and Bioformulation
Synthetic biology approach for biomanufacturing; Intelligent manufacturing of new therapeutics, 3D bioprinting, Bioproduct separation and formulations.
Medical devices for detecting infectious diseases including Covid-19 and cancer
Molecular diagnostics using the OxLAMP® technology for infectious diseases; Home screening and POC testing for early detection of cancers.
Recognition and Awards
Fellow, The Royal Academy of Engineering, 2013
International Member, Chinese Academy of Engineering, 2021
Fellow, Academy of Medical Sciences, 2023
Overall Achievement Award, The 2023 IChemE Global Award, 2023
Best Start-up Award, The 2023 IChemE Global Award, 2023
Innovative Product Award, The 2023 IChemE Global Award, 2023
President’s Special Award, The Royal Academy of Engineering, 2020
The 2010 Basil Brennan Medal, IChemE, 2011
Distinguished Visiting Professor, Tsinghua University, China (2023-2025)
Distinguished Visiting Professor, City University of Hong Kong (2024-2026)
Recent Publications
- Lim B, Yin Y, Ye H, Cui Z, Papachristodoulou A, Huang WE. Reprogramming Synthetic Cells for Targeted Cancer Therapy. ACS Synth Biol. 2022 Mar 18;11(3):1349-1360. https://doi: 10.1021/acssynbio.1c00631.
- Martin, R.; Lei, R.; Zeng, Y.; Zhu, J.; Chang, H.; Ye, H.; Cui, Z. Membrane Applications in Autologous Cell Therapy. Membranes 2022, 12, 1182. https://doi.org/10.3390/membranes12121182
- Yu, Y., Zhou, J.X.Y., Li, B., Ji, M., Wang, Y., Carnaby, E. et al. (2022) A quantitative RT-qLAMP for the detection of SARS-CoV-2 and human gene in clinical application. Microbial Biotechnology, 2022, 15 (10): 2619-2630. Available from: https://doi.org/10.1111/1751-7915.14112.
- Nguyen, L. T. B., Baudequin, T., Cui, Z., & Ye, H. (2022) Validation and scalability of homemade polycaprolactone macrobeads grafted with thermo-responsive poly(N-isopropylacrylamide) for mesenchymal stem cell expansion and harvesting. Biotechnology and Bioengineering, 119, 2345– 2358. https://doi.org/10.1002/bit.28133
- Lam C, Meinert E, Yang A, Cui Z. (2022) Impact of fast-track regulatory designations on strategic commercialization decisions for autologous cell therapies. Regen Med. 17(3):155-174. https://doi: 10.2217/rme-2021-0061.
- Hsu, C.C., Julian H George, Sharlayne Waller, Cyril Besnard, David A Nagel, Eric J Hill, Michael D Coleman, Alexander M Korsunsky, Zhanfeng Cui, Hua Ye (2022), Increased connectivity of hiPSC-derived neural networks in multiphase granular hydrogel scaffolds, Bioreactive Materials, 9:358-372, published online on 15/7/2021. doi:10.1016/j.bioactmat.2021.07.008.
- Lim, B., Jeremy Ratcliff, Dorota A Nawrot, Yejiong Yu, Harshmeena R Sanghani, Chia-Chen Hsu, Leon Peto, Simon Evans, Susanne H Hodgson, Aikaterini Skeva, Maria Adam, Maria Panopoulou, Christos E Zois, Katy Poncin, Sridhar R Vasudevan, Siqi Dai, Shuai Ren, Hong Chang, Zhanfeng Cui, Peter Simmonds, Wei E Huang, Monique I Andersson (2021), Clinical validation of optimised RT-LAMP for the diagnosis of SARS-CoV-2 infection, Sci Rep 11: 1-11. doi:10.1038/s41598-021-95607-1.
- Hsu, C C, Xu, J, Bas, B, Wang, H, Cui, Z F,Huang, W, Ye, H (2020), A single-cell Raman-based platform to identify developmental stages of human pluripotent stem cells-derived neurons, PNAS, 117 (31) 18412-18423. doi:10.1073/pnas.2001906117
- Lam, C, E. Meinert, A. Yang, Z. Cui (2021), Comparison between centralized and decentralized supply chains of autologous chimeric antigen receptor T-cell therapies: a UK case study based on discrete event simulation, Cytotherapy, 23(5):433-451. Available online 2 Mar 2021. doi:10.1016/j.jcyt.2020.08.007
- George, J., Hsu, C.C., Nguyen, L.T.B., Ye, H. and Cui, Z. (2020). Neural tissue engineering with structured hydrogels in CNS models and therapies. Biotechnology Advances. 42: 107370 doi: 10.1016/j.biotechadv.2019.03.009.
- Tayebi, L., Cui, Z. & Ye, H (2020). A tri-component knee plug for the 3rd generation of autologous chondrocyte implantation. Sci Rep 10, 17048. doi:10.1038/s41598-020-73863-x
- Cui Z, Chang H, Wang H, Lim B, Hsu CC, Yu Y, Jia H, Wang Y, Zeng Y, Ji M, Liu W (2020), Inverarity C, Huang WE. Development of a rapid test kit for SARS-CoV-2: an example of product design. Biodes Manuf. 11:1-4. doi: 10.1007/s42242-020-00075-7.
- Huang WE, Lim B, Hsu CC, Xiong D, Wu W, Yu Y, Jia H, Wang Y, Zeng Y, Ji M, Chang H, Zhang X, Wang H, Cui Z (2020). RT-LAMP for rapid diagnosis of coronavirus SARS-CoV-2. Microb Biotechnol. 13(4):950-961. doi: 10.1111/1751-7915.13586. (Wiley Top Downloaded Article in 2021)
- Fan, C, Davison, P A, Habgood, R, Zeng, H, Decker, C M, Salazar, M G, Lueangwattanapong, K, Townley, H E, Yang, A, Thompson, I P, Ye, H, Cui Z F, Schmidt, F, Hunter, C N, Huang, W E (2020), Chromosome-free bacterial cells are safe and programmable platforms for synthetic biology PNAS, 117 (12) 6752-6761. doi:10.1073/pnas.1918859117